{"id":"lidamidine","rwe":[{"pmid":"38097437","year":"2023","title":"The Mexican consensus on fecal incontinence.","finding":"","journal":"Revista de gastroenterologia de Mexico (English)","studyType":"Clinical Study"},{"pmid":"10975022","year":"2000","title":"A randomised double-blind placebo-controlled trial of lidamidine HCL in irritable bowel syndrome.","finding":"","journal":"Acta gastroenterologica Latinoamericana","studyType":"Clinical Study"},{"pmid":"9190662","year":"1997","title":"[Treatment of irritable colon with lidamidine and support psychotherapy].","finding":"","journal":"Revista de gastroenterologia de Mexico","studyType":"Clinical Study"},{"pmid":"8136086","year":"1994","title":"Adverse effects of drugs used in the management of constipation and diarrhoea.","finding":"","journal":"Drug safety","studyType":"Clinical Study"},{"pmid":"1651261","year":"1991","title":"Gastrointestinal receptors and drugs in motility disorders.","finding":"","journal":"Digestion","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Adrenergic Agents","category":"pharmacology"},{"label":"Adrenergic Agonists","category":"pharmacology"},{"label":"Antidiarrheals","category":"pharmacology"},{"label":"Gastrointestinal Agents","category":"pharmacology"},{"label":"Neurotransmitter Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["lidamidine monohydrochloride","WHR-1142A","lidamidine hydrochloride","lidamidine","lidamidine HCl"],"offLabel":[],"synonyms":["lidamidine monohydrochloride","WHR-1142A","lidamidine hydrochloride","lidamidine","lidamidine HCl"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells have locks on them, and Lidamidine has a key that fits into those locks. When it binds to the lock, it triggers a response that helps to treat a particular condition. This is a simplified explanation of how Lidamidine works at a molecular level.","oneSentence":"Lidamidine works by interacting with a specific molecular target to produce a therapeutic effect.","technicalDetail":"Lidamidine's exact mechanism of action is unknown, but it is believed to interact with a specific molecular target to produce a therapeutic effect."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1578","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=LIDAMIDINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:21:08.861382","biosimilars":[],"competitors":[],"genericName":"lidamidine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"006041","UNII":"Q8X04W8418","CHEBI":"CHEBI:134907","INN_ID":"4603","RXNORM":"28701","UMLSCUI":"C0064961","ChEMBL_ID":"CHEMBL448416","KEGG_DRUG":"D02407","PUBCHEM_CID":"47510","SECONDARY_CAS_RN":"65009-35-0","MESH_SUPPLEMENTAL_RECORD_UI":"C020918"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":45,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2023 Oct-Dec","pmid":"38097437","title":"The Mexican consensus on fecal incontinence.","journal":"Revista de gastroenterologia de Mexico (English)"},{"date":"2000","pmid":"10975022","title":"A randomised double-blind placebo-controlled trial of lidamidine HCL in irritable bowel syndrome.","journal":"Acta gastroenterologica Latinoamericana"},{"date":"1997 Jan-Mar","pmid":"9190662","title":"[Treatment of irritable colon with lidamidine and support psychotherapy].","journal":"Revista de gastroenterologia de Mexico"},{"date":"1994 Jan","pmid":"8136086","title":"Adverse effects of drugs used in the management of constipation and diarrhoea.","journal":"Drug safety"},{"date":"1991","pmid":"1651261","title":"Gastrointestinal receptors and drugs in motility disorders.","journal":"Digestion"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"LIDAMIDINE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Lidamidine is a small molecule. It is also known by the synonyms Lidamidine HCl, Lidamidine Hydrochloride, and WHR-1142A.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}