{"id":"levosert-20","safety":{"commonSideEffects":[{"rate":null,"effect":"Irregular bleeding or spotting"},{"rate":null,"effect":"Amenorrhea"},{"rate":null,"effect":"Pelvic pain or cramping"},{"rate":null,"effect":"Device expulsion"},{"rate":null,"effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Levosert-20 releases levonorgestrel, a synthetic progestin, directly into the uterine cavity at a controlled rate. This local hormonal delivery thickens cervical mucus, alters the endometrium to prevent implantation, and may inhibit sperm transport, providing contraceptive efficacy while minimizing systemic hormone exposure compared to oral contraceptives.","oneSentence":"Levosert-20 is a levonorgestrel-releasing intrauterine system designed to provide long-acting contraception and reduce menstrual bleeding.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:49:28.154Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Contraception"},{"name":"Reduction of menorrhagia (heavy menstrual bleeding)"}]},"trialDetails":[{"nctId":"NCT01695902","phase":"PHASE3","title":"Therapeutic Equivalence Trial of Two Hormonal-IUDs in Patients With Heavy Menstrual Bleeding","status":"COMPLETED","sponsor":"Uteron Pharma S.A.","startDate":"2007-12","conditions":"Heavy Menstrual Bleeding","enrollment":280}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Levosert-20","genericName":"Levosert-20","companyName":"Uteron Pharma S.A.","companyId":"uteron-pharma-s-a","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Levosert-20 is a levonorgestrel-releasing intrauterine system designed to provide long-acting contraception and reduce menstrual bleeding. Used for Contraception, Reduction of menorrhagia (heavy menstrual bleeding).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}