{"id":"levofacetoperane","rwe":[{"pmid":"14231300","year":"1964","title":"[FOREIGN PSYCHOPHARMACOLOGICAL DRUGS: LEVOFACETOPERANE (8228 RP)].","finding":"","journal":"Minerva medica","studyType":"Clinical Study"}],"tags":[{"label":"levofacetoperane","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"lidepran","offLabel":[],"synonyms":["lidepran","levophacetoperane","levofacetoperane","phacetoperane"],"timeline":[],"approvals":[],"brandName":"Lidepran","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"levofacetoperane","explanation":"Imagine your body's cells have locks on them, and Lidepran has a key that fits into one of those locks. When it binds to the lock, it triggers a series of events that help to treat a particular condition. This is a simplified explanation of how Lidepran works at a molecular level.","oneSentence":"Lidepran works by interacting with a specific molecular target to produce its therapeutic effects.","technicalDetail":"Levofacetoperane is a small molecule that binds to a specific protein target, modulating its activity and producing its therapeutic effects."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Levophacetoperane","title":"Levophacetoperane","extract":"Levophacetoperane is a psychostimulant developed by Rhône-Poulenc in the 1950s. The drug has been used as an antidepressant and anorectic. It is the reverse ester of methylphenidate. Phacetoperane and levophacetoperane have been used as wakefulness-promoting agents in the treatment of narcolepsy."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3319","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=LEVOFACETOPERANE","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Levophacetoperane","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T14:06:26.451849","biosimilars":[],"competitors":[],"genericName":"levofacetoperane","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"3SZ9ZII529","CHEBI":"CHEBI:134950","INN_ID":"1157","UMLSCUI":"C0064875","ChEMBL_ID":"CHEMBL2104874","PUBCHEM_CID":"15706387","MESH_SUPPLEMENTAL_RECORD_UI":"C010500"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"1964 Oct 31","pmid":"14231300","title":"[FOREIGN PSYCHOPHARMACOLOGICAL DRUGS: LEVOFACETOPERANE (8228 RP)].","journal":"Minerva medica"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Lidepran is a small molecule with the synonyms LEVOFACETOPERANE, LEVOFACETOPERANO, LEVOPHACETOPERANE, and RP-8228.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}