{"id":"levocarnitine-propionate","rwe":[{"pmid":"41867210","year":"2026","title":"Multi-Omics Integration of Transcriptomics and Metabolomics with Machine Learning Uncovers Novel Risk Factors for Alzheimer's disease.","finding":"","journal":"medRxiv : the preprint server for health sciences","studyType":"Clinical Study"},{"pmid":"41828410","year":"2026","title":"Integrated Untargeted and Targeted Metabolomics Reveals Distinct Bioactive Metabolite Profiles Between Probiotic Supplements and Yogurt.","finding":"","journal":"International journal of molecular sciences","studyType":"Clinical Study"},{"pmid":"41753565","year":"2026","title":"Dietary Supplementation of Concentrate Improves Lactation Performance and Immune Function in Grazing Lactating Yaks Through Changes in Rumen Microbial Population and Metabolites.","finding":"","journal":"Microorganisms","studyType":"Clinical Study"},{"pmid":"41724378","year":"2026","title":"Association between the gut microbiota and estimated glomerular filtration rate in two Swedish population-based cohorts.","finding":"","journal":"Kidney international","studyType":"Clinical Study"},{"pmid":"41584689","year":"2026","title":"Dietary sodium propionate optimizes intestinal microbiota and promotes growth performance, lipid metabolism and ammonia tolerance in yellow catfish (Pelteobagrus fulvidraco).","finding":"","journal":"Animal nutrition (Zhongguo xu mu shou yi xue hui)","studyType":"Clinical Study"}],"tags":[{"label":"Carnitine Analog","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["levocarnitine propionate","levocarnitine propionate hydrochloride","levocarnitine propionate HCl"],"offLabel":[],"synonyms":["levocarnitine propionate","levocarnitine propionate hydrochloride","levocarnitine propionate HCl"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"Carnitine Analog","explanation":"Think of levocarnitine propionate like a delivery truck that brings fatty acids to the power plants in our cells, called mitochondria. This helps our cells produce energy more efficiently, which can be especially important for people with certain medical conditions. By increasing the levels of levocarnitine, levocarnitine propionate can help improve energy production and reduce fatigue.","oneSentence":"Levocarnitine propionate works by increasing the levels of levocarnitine in the body, which helps to transport fatty acids into the mitochondria for energy production.","technicalDetail":"Levocarnitine propionate acts as a prodrug, which is converted into levocarnitine in the body. Levocarnitine then binds to carnitine palmitoyltransferase 1 (CPT1), facilitating the transport of long-chain fatty acids into the mitochondria for beta-oxidation and energy production."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4040","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=levocarnitine propionate","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T14:06:13.486992","biosimilars":[],"competitors":[],"genericName":"levocarnitine propionate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"10540","NDDF":"003576","UNII":"0HU2UI27HF","CHEBI":"CHEBI:16347","VANDF":"4018934","INN_ID":"6098","RXNORM":"42955","UMLSCUI":"C5440668","ChEMBL_ID":"CHEMBL1516469","KEGG_DRUG":"D04713","DRUGBANK_ID":"DB15980","PUBCHEM_CID":"188824","SNOMEDCT_US":"329486002","SECONDARY_CAS_RN":"119793-66-7","MESH_DESCRIPTOR_UI":"D002331"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"pharmacokinetics":{"source":"DrugCentral","halfLife":"1.28 hours","clearance":"2.33 mL/min/kg","volumeOfDistribution":"0.3 L/kg"},"publicationCount":216,"therapeuticAreas":["Gastroenterology"],"biosimilarFilings":[],"recentPublications":[{"date":"2026 Mar 3","pmid":"41867210","title":"Multi-Omics Integration of Transcriptomics and Metabolomics with Machine Learning Uncovers Novel Risk Factors for Alzheimer's disease.","journal":"medRxiv : the preprint server for health sciences"},{"date":"2026 Feb 26","pmid":"41828410","title":"Integrated Untargeted and Targeted Metabolomics Reveals Distinct Bioactive Metabolite Profiles Between Probiotic Supplements and Yogurt.","journal":"International journal of molecular sciences"},{"date":"2026 Jan 24","pmid":"41753565","title":"Dietary Supplementation of Concentrate Improves Lactation Performance and Immune Function in Grazing Lactating Yaks Through Changes in Rumen Microbial Population and Metabolites.","journal":"Microorganisms"},{"date":"2026 Feb 20","pmid":"41724378","title":"Association between the gut microbiota and estimated glomerular filtration rate in two Swedish population-based cohorts.","journal":"Kidney international"},{"date":"2026 Mar","pmid":"41584689","title":"Dietary sodium propionate optimizes intestinal microbiota and promotes growth performance, lipid metabolism and ammonia tolerance in yellow catfish (Pelteobagrus fulvidraco).","journal":"Animal nutrition (Zhongguo xu mu shou yi xue hui)"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"levocarnitine propionate","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Levocarnitine propionate is a carnitine analog, a small molecule drug that has been developed to target a specific condition. However, the target and approved indications for levocarnitine propionate are currently unknown. The drug has a half-life of 1.28 hours, but its bioavailability and commercial status are not well-documented. As a result, levocarnitine propionate is not widely recognized as a treatment option. Further research is needed to fully understand its potential benefits and risks.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}