{"id":"leo-80190-vehicle","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL2108661","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"As a vehicle formulation rather than an active drug, LEO 80190 Vehicle functions as a delivery system to optimize penetration and retention of therapeutic agents in the skin. The specific composition and mechanism of enhancement are proprietary to LEO Pharma and are designed to support efficacy of the active ingredient when combined in a final formulation.","oneSentence":"LEO 80190 Vehicle is a topical formulation vehicle designed to enhance dermal delivery of active pharmaceutical ingredients.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:18:31.170Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dermatological conditions (specific indication dependent on active ingredient combined with vehicle)"}]},"trialDetails":[{"nctId":"NCT00691002","phase":"PHASE3","title":"Efficacy and Safety of Calcipotriol Plus Hydrocortisone Ointment in Psoriasis Vulgaris on the Face and Skin Folds","status":"COMPLETED","sponsor":"LEO Pharma","startDate":"2008-05","conditions":"Psoriasis Vulgaris","enrollment":1245}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"LEO 80190 Vehicle","genericName":"LEO 80190 Vehicle","companyName":"LEO Pharma","companyId":"leo-pharma","modality":"Small molecule","firstApprovalDate":"","aiSummary":"LEO 80190 Vehicle is a topical formulation vehicle designed to enhance dermal delivery of active pharmaceutical ingredients. Used for Dermatological conditions (specific indication dependent on active ingredient combined with vehicle).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}