{"id":"leo-80185-vehicle","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL2108661","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"As a vehicle formulation, LEO 80185 serves as the inactive carrier system for topical drug delivery, optimizing penetration and retention of the active ingredient at the site of application. The specific mechanism depends on the active drug combined with this vehicle, which is not specified in the available information.","oneSentence":"LEO 80185 vehicle is a topical formulation designed to deliver active pharmaceutical ingredients to the skin.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:18:36.319Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dermatological conditions (specific indication unknown)"}]},"trialDetails":[{"nctId":"NCT01188928","phase":"PHASE3","title":"LEO 80185 in the Treatment of Psoriasis Vulgaris on the Non-scalp Regions of the Body (Trunk and/or Limbs)","status":"COMPLETED","sponsor":"LEO Pharma","startDate":"2010-09","conditions":"Psoriasis Vulgaris","enrollment":1152},{"nctId":"NCT00670241","phase":"PHASE3","title":"Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel Compared With Tacalcitol Ointment and the Gel Vehicle Alone in Patients With Psoriasis Vulgaris","status":"COMPLETED","sponsor":"LEO Pharma","startDate":"2008-04","conditions":"Psoriasis Vulgaris","enrollment":458},{"nctId":"NCT00263718","phase":"PHASE2","title":"Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel in Psoriasis Vulgaris","status":"COMPLETED","sponsor":"LEO Pharma","startDate":"2005-12","conditions":"Psoriasis Vulgaris","enrollment":360},{"nctId":"NCT02379793","phase":"PHASE1","title":"Skin Irritation Test of LEO 80185 Gel in Healthy Japanese Subjects","status":"COMPLETED","sponsor":"LEO Pharma","startDate":"2015-03","conditions":"Skin and Connective Tissue Diseases","enrollment":33}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"LEO 80185 vehicle","genericName":"LEO 80185 vehicle","companyName":"LEO Pharma","companyId":"leo-pharma","modality":"Small molecule","firstApprovalDate":"","aiSummary":"LEO 80185 vehicle is a topical formulation designed to deliver active pharmaceutical ingredients to the skin. Used for Dermatological conditions (specific indication unknown).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}