{"id":"lefetamine","rwe":[{"pmid":"31152702","year":"2019","title":"Pharmacological characterizations of the 'legal high' fluorolintane and isomers.","finding":"","journal":"European journal of pharmacology","studyType":"Clinical Study"},{"pmid":"29956843","year":"2018","title":"Ephenidine, diphenidine, and methoxphenidine complications reported to the French Addictovigilance Network.","finding":"","journal":"Fundamental & clinical pharmacology","studyType":"Clinical Study"},{"pmid":"27552699","year":"2016","title":"An overview of emerging and new psychoactive substances in the United Kingdom.","finding":"","journal":"Forensic science international","studyType":"Clinical Study"},{"pmid":"27314670","year":"2016","title":"Pharmacological Investigations of the Dissociative 'Legal Highs' Diphenidine, Methoxphenidine and Analogues.","finding":"","journal":"PloS one","studyType":"Clinical Study"},{"pmid":"26276083","year":"2015","title":"Toxicokinetics of lefetamine and derived diphenylethylamine designer drugs-Contribution of human cytochrome P450 isozymes to their main phase I metabolic steps.","finding":"","journal":"Toxicology letters","studyType":"Clinical Study"}],"tags":[{"label":"lefetamine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"lephetamine","offLabel":[],"synonyms":["lefetamine hydrochloride","lefetamine","lephetamine","lefetamine HCl"],"timeline":[],"approvals":[],"brandName":"Lephetamine","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"lefetamine","explanation":"Imagine your body's cells have locks on them, and lefetamine is a key that fits into one of these locks. When it binds to the lock, it can either unlock the cell or block something from getting in. This can affect how the cell works and communicate with other cells, but the details of how it does this are still a mystery.","oneSentence":"Lefetamine is thought to work by interacting with a specific target in the body, although the exact nature of this interaction is not well understood.","technicalDetail":"Lefetamine is a small molecule that binds to a specific target, although the identity of this target is currently unknown. This binding event is thought to trigger a cascade of downstream effects that ultimately lead to the drug's therapeutic or adverse effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3316","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=LEFETAMINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T14:04:58.659702","biosimilars":[],"competitors":[],"genericName":"lefetamine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"4J9726V5Y9","CHEBI":"CHEBI:31768","INN_ID":"3457","UMLSCUI":"C0064766","ChEMBL_ID":"CHEMBL3185938","KEGG_DRUG":"D01411","PUBCHEM_CID":"443970","SECONDARY_CAS_RN":"14148-99-3","MESH_SUPPLEMENTAL_RECORD_UI":"C011896"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":19,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2019 Aug 15","pmid":"31152702","title":"Pharmacological characterizations of the 'legal high' fluorolintane and isomers.","journal":"European journal of pharmacology"},{"date":"2018 Dec","pmid":"29956843","title":"Ephenidine, diphenidine, and methoxphenidine complications reported to the French Addictovigilance Network.","journal":"Fundamental & clinical pharmacology"},{"date":"2016 Oct","pmid":"27552699","title":"An overview of emerging and new psychoactive substances in the United Kingdom.","journal":"Forensic science international"},{"date":"2016","pmid":"27314670","title":"Pharmacological Investigations of the Dissociative 'Legal Highs' Diphenidine, Methoxphenidine and Analogues.","journal":"PloS one"},{"date":"2015 Nov 4","pmid":"26276083","title":"Toxicokinetics of lefetamine and derived diphenylethylamine designer drugs-Contribution of human cytochrome P450 isozymes to their main phase I metabolic steps.","journal":"Toxicology letters"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Lephetamine is a small molecule. It is also known as Levetiracetam or Levetiracetam's synonym Levetiracetam's synonym is Levetiracetam, however, another synonym is LEFETAMINA or LEFETAMINE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}