{"id":"lansoprazole-lanton","safety":{"commonSideEffects":[{"rate":"12-15%","effect":"Headache"},{"rate":"8-10%","effect":"Diarrhea"},{"rate":"5-8%","effect":"Abdominal pain"},{"rate":"4-6%","effect":"Nausea"},{"rate":"3-5%","effect":"Constipation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Lansoprazole is a proton pump inhibitor (PPI) that irreversibly binds to and inactivates the H+/K+-ATPase enzyme on the secretory surface of gastric parietal cells. This blocks the final step of gastric acid production, significantly reducing both basal and stimulated acid secretion. It is used to treat acid-related gastrointestinal disorders by maintaining elevated gastric pH.","oneSentence":"Lansoprazole inhibits the proton pump in gastric parietal cells, reducing gastric acid secretion.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:51:43.544Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Gastroesophageal reflux disease (GERD)"},{"name":"Peptic ulcer disease"},{"name":"Zollinger-Ellison syndrome"},{"name":"Erosive esophagitis"}]},"trialDetails":[{"nctId":"NCT00825630","phase":"PHASE4","title":"13-C Urea Breath Test Using BreathID System and PPIs (Proton Pump Inhibitors)","status":"COMPLETED","sponsor":"Meridian Bioscience, Inc.","startDate":"2008-11","conditions":"Helicobacter Pylori Infection","enrollment":123}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Lanton"],"phase":"marketed","status":"active","brandName":"Lansoprazole (Lanton)","genericName":"Lansoprazole (Lanton)","companyName":"Meridian Bioscience, Inc.","companyId":"meridian-bioscience-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Lansoprazole inhibits the proton pump in gastric parietal cells, reducing gastric acid secretion. Used for Gastroesophageal reflux disease (GERD), Peptic ulcer disease, Zollinger-Ellison syndrome.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}