{"id":"lanoconazole","rwe":[],"tags":[{"label":"lanoconazole","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"D01AC22","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"latoconazole","offLabel":[],"synonyms":["lanoconazole","latoconazole","NND-318"],"timeline":[],"approvals":[],"brandName":"Latoconazole","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"lanoconazole","explanation":"Think of it like a building block of a house. Ergosterol is like a brick that helps hold the fungal cell together. When lanoconazole blocks its production, the cell can't repair itself and eventually dies.","oneSentence":"Lanoconazole works by blocking the production of ergosterol, a key component of fungal cell membranes.","technicalDetail":"Lanoconazole inhibits the enzyme lanosterol 14α-demethylase, which is essential for the conversion of lanosterol to ergosterol in the fungal cell membrane."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3979","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=LANOCONAZOLE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:14:50.891482","biosimilars":[],"competitors":[{"drugName":"clotrimazole","drugSlug":"clotrimazole","fdaApproval":"1975-02-03","patentExpiry":"May 26, 2042","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"miconazole","drugSlug":"miconazole","fdaApproval":"1974-01-08","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"econazole","drugSlug":"econazole","fdaApproval":"1982-12-23","patentExpiry":"Aug 8, 2031","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"thiabendazole","drugSlug":"thiabendazole","fdaApproval":"1967-04-07","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"tioconazole","drugSlug":"tioconazole","fdaApproval":"1983-02-18","genericCount":1,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"ketoconazole","drugSlug":"ketoconazole","fdaApproval":"1981-06-12","genericCount":19,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"sulconazole","drugSlug":"sulconazole","fdaApproval":"1985-08-30","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"oxiconazole","drugSlug":"oxiconazole","fdaApproval":"1988-12-30","genericCount":1,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"sertaconazole","drugSlug":"sertaconazole","fdaApproval":"2003-12-10","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"fluconazole","drugSlug":"fluconazole","fdaApproval":"1990-01-29","genericCount":31,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"luliconazole","drugSlug":"luliconazole","fdaApproval":"2013-11-14","patentExpiry":"Sep 6, 2033","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"efinaconazole","drugSlug":"efinaconazole","fdaApproval":"2014-06-06","patentExpiry":"Oct 24, 2030","patentStatus":"Patent protected","relationship":"same-class"}],"genericName":"lanoconazole","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"clotrimazole","brandName":"clotrimazole","genericName":"clotrimazole","approvalYear":"1975","relationship":"same-class"},{"drugId":"miconazole","brandName":"miconazole","genericName":"miconazole","approvalYear":"1974","relationship":"same-class"},{"drugId":"econazole","brandName":"econazole","genericName":"econazole","approvalYear":"1982","relationship":"same-class"},{"drugId":"thiabendazole","brandName":"thiabendazole","genericName":"thiabendazole","approvalYear":"1967","relationship":"same-class"},{"drugId":"tioconazole","brandName":"tioconazole","genericName":"tioconazole","approvalYear":"1983","relationship":"same-class"},{"drugId":"ketoconazole","brandName":"ketoconazole","genericName":"ketoconazole","approvalYear":"1981","relationship":"same-class"},{"drugId":"sulconazole","brandName":"sulconazole","genericName":"sulconazole","approvalYear":"1985","relationship":"same-class"},{"drugId":"oxiconazole","brandName":"oxiconazole","genericName":"oxiconazole","approvalYear":"1988","relationship":"same-class"},{"drugId":"sertaconazole","brandName":"sertaconazole","genericName":"sertaconazole","approvalYear":"2003","relationship":"same-class"},{"drugId":"fluconazole","brandName":"fluconazole","genericName":"fluconazole","approvalYear":"1990","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"015255","UNII":"4E7858311F","CHEBI":"CHEBI:31761","INN_ID":"6853","UMLSCUI":"C0125333","ChEMBL_ID":"CHEMBL1555126","KEGG_DRUG":"D01092","PUBCHEM_CID":"3002820","MESH_SUPPLEMENTAL_RECORD_UI":"C072774"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":72,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"D01AC22","allCodes":["D01AC22"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Latoconazole is a small molecule. It is also known by the synonyms ASTAT, LANOCONAZOL, and LANOCONAZOLE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}