{"id":"landmark-guided-erector-spinae-block","safety":{"commonSideEffects":[{"rate":null,"effect":"Local anesthetic toxicity"},{"rate":null,"effect":"Pneumothorax"},{"rate":null,"effect":"Vascular puncture"},{"rate":null,"effect":"Nerve injury"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The Erector Spinae Block is a regional anesthesia procedure that uses anatomical landmarks to guide injection of local anesthetic around the erector spinae muscle group in the posterior trunk. This blocks sensory and motor nerves in the thoracic and abdominal wall, providing perioperative analgesia and reducing the need for systemic opioids. The technique is being evaluated in Phase 3 trials for efficacy and safety in various surgical applications.","oneSentence":"A landmark-guided regional anesthesia technique that blocks the erector spinae muscles to provide pain relief for thoracic and abdominal procedures.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:49:14.006Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Perioperative pain management for thoracic and abdominal surgery"}]},"trialDetails":[{"nctId":"NCT07469410","phase":"PHASE3","title":"Comparison of Postoperative Analgesia in Erector Spinae Plane Block (ESPB) v/s Subcostal Transversus Abdominal Plane Block (STAP) in Adults Undergoing Laparoscopic Cholecystectomy.","status":"COMPLETED","sponsor":"Patel Hospital, Pakistan","startDate":"2025-06-01","conditions":"Postoperative Analgesia","enrollment":60},{"nctId":"NCT07108959","phase":"NA","title":"ESPB Versus Perioperative Iv Lidocaine Infusion on Proinflammatory Cytokines in Breast Cancer Surgeries","status":"NOT_YET_RECRUITING","sponsor":"Alexandria University","startDate":"2025-08-01","conditions":"Breast Cancer, ESPB, Lidocaine Infusion","enrollment":40},{"nctId":"NCT06771466","phase":"NA","title":"Post-c-section Pain Control Satisfaction with Erector Spinae Simple Block Vs Lateral Quadratus Lumborum Block","status":"NOT_YET_RECRUITING","sponsor":"Wael Sayed El Gharabawy","startDate":"2025-03","conditions":"Satisfaction, Pain Management After Surgery","enrollment":126},{"nctId":"NCT06246292","phase":"NA","title":"The Efficacy and Safety of Landmark-guided Compared to Ultrasound-guided Erector Spinae Plane Block Techniques for Analgesia in Female Patients After Breast Surgery.","status":"COMPLETED","sponsor":"Alexandria University","startDate":"2024-02-10","conditions":"Nerve Block","enrollment":248},{"nctId":"NCT04223700","phase":"NA","title":"Ultrasound-guided Thoracic Spinal Level Identification","status":"UNKNOWN","sponsor":"Seoul National University","startDate":"2020-01-13","conditions":"Thoracic Diseases, Myofascial Pain","enrollment":100}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Landmark guided Erector Spinae Block","genericName":"Landmark guided Erector Spinae Block","companyName":"Patel Hospital, Pakistan","companyId":"patel-hospital-pakistan","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A landmark-guided regional anesthesia technique that blocks the erector spinae muscles to provide pain relief for thoracic and abdominal procedures. Used for Perioperative pain management for thoracic and abdominal surgery.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}