{"id":"laminaria-tent","safety":{"commonSideEffects":[{"rate":null,"effect":"Cramping or abdominal discomfort"},{"rate":null,"effect":"Vaginal bleeding or spotting"},{"rate":null,"effect":"Infection or endometritis"},{"rate":null,"effect":"Incomplete dilation"},{"rate":null,"effect":"Cervical laceration"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Laminaria tents are sterile, dehydrated stems of the laminaria plant that are inserted into the cervical canal. As they absorb cervical and uterine fluids, they expand gradually over 12-24 hours, mechanically dilating the cervix without pharmacological action. This allows for safer access to the uterine cavity for procedures such as dilation and curettage, hysteroscopy, or abortion.","oneSentence":"Laminaria tent is a mechanical cervical dilator made from dried seaweed that absorbs moisture and gradually expands to dilate the cervix.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:51:35.762Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cervical dilation prior to gynecological procedures"},{"name":"Preparation for dilation and curettage"},{"name":"Cervical preparation for hysteroscopy"},{"name":"Cervical dilation for induced abortion"}]},"trialDetails":[{"nctId":"NCT07465016","phase":"PHASE4","title":"Laminaria Japonicum Followed by Misoprostol Versus Misoprostol Alone for Mid-Trimester Abortion Induction in Scarred Uterus","status":"COMPLETED","sponsor":"Pavly Maged Jimmy Fouad","startDate":"2023-01-10","conditions":"Induction of Abortion, Scarred Uterus","enrollment":60},{"nctId":"NCT06151925","phase":"NA","title":"Laminaria Tents Versus Vaginal Prostaglandin in Cervical Ripening","status":"COMPLETED","sponsor":"Ain Shams University","startDate":"2022-10-01","conditions":"Labor Onset and Length Abnormalities","enrollment":90},{"nctId":"NCT03388827","phase":"PHASE2","title":"Laminaria and Misoprostol Before Operative Hysteroscopy","status":"UNKNOWN","sponsor":"Zagazig University","startDate":"2017-12-20","conditions":"Cervical Spasm","enrollment":100},{"nctId":"NCT01597726","phase":"NA","title":"Cervical Priming Before Dilation & Evacuation","status":"COMPLETED","sponsor":"Ibis Reproductive Health","startDate":"2012-05","conditions":"Abortion, Induced","enrollment":159},{"nctId":"NCT01678703","phase":"NA","title":"Comparison of Laminaria and Misoprostol for Cervical Preparation Before Second Trimester Surgical Abortion","status":"COMPLETED","sponsor":"Wolfson Medical Center","startDate":"2007-11","conditions":"Induced; Abortion, Nonmedical","enrollment":84}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":79,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Laminaria Tent","genericName":"Laminaria Tent","companyName":"Pavly Maged Jimmy Fouad","companyId":"pavly-maged-jimmy-fouad","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Laminaria tent is a mechanical cervical dilator made from dried seaweed that absorbs moisture and gradually expands to dilate the cervix. Used for Cervical dilation prior to gynecological procedures (dilation and curettage, hysteroscopy, abortion), Cervical ripening prior to labor induction.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}