{"id":"lactobacillus-casei-variety-rhamnosus-granules","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal disturbance"},{"rate":null,"effect":"Bloating"},{"rate":null,"effect":"Flatulence"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This live biotherapeutic product works by restoring beneficial bacterial populations in the gastrointestinal tract, which helps maintain intestinal barrier function, promotes the growth of other beneficial microorganisms, and stimulates local and systemic immune responses. The strain produces metabolites and interacts with intestinal epithelial cells and immune cells to support digestive health and immune homeostasis.","oneSentence":"Lactobacillus casei variety rhamnosus is a probiotic bacterium that colonizes the gut and modulates the intestinal microbiota and immune system.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:33:48.658Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Gastrointestinal health maintenance"},{"name":"Diarrhea prevention and treatment"},{"name":"Immune system support"}]},"trialDetails":[{"nctId":"NCT01792739","phase":"PHASE4","title":"Lactobacillus Preparation on the Incidence of Diarrhea","status":"UNKNOWN","sponsor":"Seoul National University Hospital","startDate":"2010-11","conditions":"Diarrhea, Death, Pneumonia","enrollment":124}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["RAMNOS GRANULS"],"phase":"marketed","status":"active","brandName":"Lactobacillus casei variety rhamnosus granules","genericName":"Lactobacillus casei variety rhamnosus granules","companyName":"Seoul National University Hospital","companyId":"seoul-national-university-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Lactobacillus casei variety rhamnosus is a probiotic bacterium that colonizes the gut and modulates the intestinal microbiota and immune system. Used for Gastrointestinal health maintenance, Diarrhea prevention and treatment, Immune system support.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}