{"id":"lactase-oral-tablets","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal distress (if inadequate dosing)"},{"rate":null,"effect":"Allergic reactions (rare)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Lactase deficiency leads to lactose intolerance, where undigested lactose causes osmotic diarrhea and fermentation-related gas and bloating. Oral lactase enzyme supplementation provides exogenous enzyme activity to hydrolyze lactose in the intestinal lumen before it can cause symptoms. This allows individuals with lactase deficiency to tolerate dairy products without gastrointestinal distress.","oneSentence":"Lactase is an enzyme that breaks down lactose (milk sugar) into glucose and galactose for absorption in the small intestine.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:49:13.026Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Lactose intolerance management"}]},"trialDetails":[{"nctId":"NCT07465562","phase":"NA","title":"Galactol® Enzyme Supplement for Post-Prandial Abdominal Bloating in Irritable Bowel Syndrome","status":"NOT_YET_RECRUITING","sponsor":"Liaquat University of Medical & Health Sciences","startDate":"2026-03-16","conditions":"Irritable Bowel Syndrome, Abdominal Bloating","enrollment":300},{"nctId":"NCT01145586","phase":"PHASE3","title":"A Non-inferiority, Multicenter and Randomized, Multiple-Dose Study About a Treatment to Hypolactasia","status":"COMPLETED","sponsor":"Eurofarma Laboratorios S.A.","startDate":"2011-06","conditions":"Lactose Intolerance","enrollment":140}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Lactase Oral Tablets","genericName":"Lactase Oral Tablets","companyName":"Eurofarma Laboratorios S.A.","companyId":"eurofarma-laboratorios-s-a","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Lactase is an enzyme that breaks down lactose (milk sugar) into glucose and galactose for absorption in the small intestine. Used for Lactose intolerance management.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}