{"id":"l-c-maxillary-anesthesia","safety":{"commonSideEffects":[{"rate":null,"effect":"Transient paresthesia"},{"rate":null,"effect":"Allergic reaction"},{"rate":null,"effect":"Injection site discomfort"},{"rate":null,"effect":"Systemic toxicity (if overdosed)"}]},"_chembl":{"chemblId":"CHEMBL265747","moleculeType":"Protein","molecularWeight":"3032.60"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This drug combines local anesthetic agents (likely lidocaine and another agent such as articaine or prilocaine, indicated by 'L+C') to achieve rapid onset and sustained duration of anesthesia in maxillary dental and oral surgical procedures. The combination formulation aims to optimize both the speed of anesthetic effect and the duration of pain relief in the upper jaw region.","oneSentence":"L+C maxillary anesthesia is a local anesthetic formulation designed to provide regional anesthesia in the maxillary region of the oral cavity.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:18:05.058Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Maxillary regional anesthesia for dental and oral surgical procedures"}]},"trialDetails":[{"nctId":"NCT02371759","phase":"PHASE3","title":"Lidocaine + Clonidine for Intraoral Anesthesia in Patients With Diabetes Mellitus Type 2","status":"COMPLETED","sponsor":"University of Belgrade","startDate":"2013-06","conditions":"Diabetes Mellitus, Local Anesthesia","enrollment":256}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"L+C maxillary anesthesia","genericName":"L+C maxillary anesthesia","companyName":"University of Belgrade","companyId":"university-of-belgrade","modality":"Small molecule","firstApprovalDate":"","aiSummary":"L+C maxillary anesthesia is a local anesthetic formulation designed to provide regional anesthesia in the maxillary region of the oral cavity. Used for Maxillary regional anesthesia for dental and oral surgical procedures.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}