{"id":"l-c-mandibular-anesthesia","safety":{"commonSideEffects":[{"rate":null,"effect":"Transient paresthesia"},{"rate":null,"effect":"Hematoma at injection site"},{"rate":null,"effect":"Allergic reaction"}]},"_chembl":{"chemblId":"CHEMBL265747","moleculeType":"Protein","molecularWeight":"3032.60"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This is a combination local anesthetic preparation intended for mandibular nerve block administration in the oral and maxillofacial region. The formulation likely combines two local anesthetic agents to achieve rapid onset and prolonged duration of sensory blockade in the distribution of the mandibular division of the trigeminal nerve, enabling pain-free dental and surgical interventions.","oneSentence":"L+C mandibular anesthesia is a local anesthetic formulation designed to provide regional anesthesia of the mandibular nerve for dental and oral surgical procedures.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:46:16.574Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Mandibular nerve block for dental anesthesia"},{"name":"Regional anesthesia for oral and maxillofacial surgery"}]},"trialDetails":[{"nctId":"NCT02371759","phase":"PHASE3","title":"Lidocaine + Clonidine for Intraoral Anesthesia in Patients With Diabetes Mellitus Type 2","status":"COMPLETED","sponsor":"University of Belgrade","startDate":"2013-06","conditions":"Diabetes Mellitus, Local Anesthesia","enrollment":256}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"L+C mandibular anesthesia","genericName":"L+C mandibular anesthesia","companyName":"University of Belgrade","companyId":"university-of-belgrade","modality":"Small molecule","firstApprovalDate":"","aiSummary":"L+C mandibular anesthesia is a local anesthetic formulation designed to provide regional anesthesia of the mandibular nerve for dental and oral surgical procedures. Used for Mandibular nerve block for dental anesthesia, Regional anesthesia for oral and maxillofacial surgery.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}