{"id":"k-cab","rwe":[],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Wonkwang University Hospital","category":"company"}],"phase":"marketed","safety":{},"trials":[],"aliases":[],"company":"Wonkwang University Hospital","patents":[],"pricing":[],"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=K-CAB","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T01:01:26.882536+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T01:01:33.386428+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=K-CAB","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T01:01:34.135368+00:00"},"crossReferences.chemblId":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL216528/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-20T01:01:35.059917+00:00"}},"allNames":["k-cab"],"offLabel":[],"synonyms":[],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"","oneSentence":"","technicalDetail":"Unfortunately, the technical details of K-cab's mechanism of action are not available."},"commercial":{},"references":[{"id":1,"url":"https://clinicaltrials.gov/search?intr=k-cab","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=k-cab","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-31T10:24:48.017367","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T01:01:37.247127+00:00","fieldsConflicting":1,"overallConfidence":0.8},"biosimilars":[],"competitors":[],"genericName":"k-cab","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[{"nctId":"NCT07497893","phase":"NA","title":"FENOX Trial (Comparative Effectiveness of Fexuprazan Co-therapy in Patients Receiving Non-Vitamin K Antagonist Oral Anticoagulants)","status":"NOT_YET_RECRUITING","sponsor":"Ewha Womans University Mokdong Hospital","startDate":"2026-12-01","conditions":["Atrial Fibrillation (AF)","Upper Gastrointestinal Bleeding (UGIB)","Gastrointestinal Hemorrhage (Clinically Important, Upper)","Drug-Related Side Effects and Adverse Reactions"],"enrollment":1000,"completionDate":"2032-11-30"},{"nctId":"NCT07277712","phase":"PHASE1","title":"A Study to Evaluate the Pharmacokinetics and Food-effect of IN-M00002 Tablet in Healthy Adult Volunteers","status":"NOT_YET_RECRUITING","sponsor":"HK inno.N Corporation","startDate":"2025-12-27","conditions":["Healthy Volunteer"],"enrollment":74,"completionDate":"2026-09-30"},{"nctId":"NCT06743243","phase":"PHASE4","title":"Effect of Tegoprazan for Elective Surgery Patients Under General Anesthesia","status":"ENROLLING_BY_INVITATION","sponsor":"Seok Kyeong Oh","startDate":"2025-07-23","conditions":["General Anesthesia"],"enrollment":174,"completionDate":"2026-12-30"},{"nctId":"NCT04844424","phase":"PHASE1","title":"A Study of JNJ-70033093 (Milvexian) in Healthy Adult Participants","status":"COMPLETED","sponsor":"Janssen Research & Development, LLC","startDate":"2021-04-14","conditions":["Healthy"],"enrollment":115,"completionDate":"2022-07-12"},{"nctId":"NCT05907798","phase":"NA","title":"Serratus Anterior Plan Block (SAP) and Pectoralis (PECSI-II) Blocks on Left Internal Mammarian Artery (LIMA) Blood Flow","status":"COMPLETED","sponsor":"Yuzuncu Yil University","startDate":"2023-01-02","conditions":["Chest Wall Blocks"],"enrollment":90,"completionDate":"2024-12-01"},{"nctId":"NCT04053816","phase":"PHASE3","title":"Prevention of Dysrhythmias on the Cardiac Intensive Care Unit - Does Maintenance of High-normal Serum Potassium Levels Matter","status":"COMPLETED","sponsor":"Barts & The London NHS Trust","startDate":"2020-10-20","conditions":["Arrhythmias, Cardiac"],"enrollment":1684,"completionDate":"2024-06-26"},{"nctId":"NCT06332638","phase":"PHASE1","title":"PK, PD and Safety of Tegoprazan 12.5 mg After Oral Administration in Healthy Subjects","status":"ENROLLING_BY_INVITATION","sponsor":"HK inno.N Corporation","startDate":"2024-03-19","conditions":["Healthy"],"enrollment":36,"completionDate":"2024-07-31"},{"nctId":"NCT06164834","phase":"PHASE1","title":"Effect of Tegoprazan on Pharmacodynamics of Clopidogrel in Healthy Subjects","status":"UNKNOWN","sponsor":"HK inno.N Corporation","startDate":"2023-12-05","conditions":["Healthy"],"enrollment":48,"completionDate":"2024-11"},{"nctId":"NCT05723510","phase":"PHASE1","title":"PK and PD Interaction Between Tegoprazan and NOACs After Multiple Oral Dosing in Healthy Volunteers","status":"COMPLETED","sponsor":"HK inno.N Corporation","startDate":"2023-03-06","conditions":["Healthy"],"enrollment":87,"completionDate":"2023-07-24"},{"nctId":"NCT05786807","phase":"PHASE4","title":"Effect of H. Pylori Eradication on Alleviating Symptoms in Functional Dyspepsia Patients","status":"UNKNOWN","sponsor":"Wonkwang University Hospital","startDate":"2022-03-07","conditions":["Helicobacter Pylori-positive With Functional Dyspepsia"],"enrollment":315,"completionDate":"2023-12-31"},{"nctId":"NCT05353010","phase":"PHASE1","title":"A Study to Evaluate Effect of IN-A001 on Pharmacokinetics of Tacrolimus in Healthy Volunteers","status":"UNKNOWN","sponsor":"HK inno.N Corporation","startDate":"2022-05-01","conditions":["Healthy"],"enrollment":12,"completionDate":"2022-11-01"},{"nctId":"NCT04568772","phase":"PHASE1","title":"Study to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy Volunteers","status":"COMPLETED","sponsor":"Seoul National University Hospital","startDate":"2020-11-25","conditions":["Gastroesophageal Reflux Disease"],"enrollment":19,"completionDate":"2021-08-03"},{"nctId":"NCT04654078","phase":"PHASE1","title":"Study to Evaluate the Pharmacokinetic Characteristics and Safety of IN-C004 in Healthy Volunteers","status":"COMPLETED","sponsor":"HK inno.N Corporation","startDate":"2021-01-18","conditions":["Healthy"],"enrollment":48,"completionDate":"2021-02-15"},{"nctId":"NCT04221321","phase":"PHASE1","title":"Effect of Tegoprazan or RAPA114 on Pharmacokinetic of Atorvastatin in Healthy Adult Volunteers","status":"COMPLETED","sponsor":"HK inno.N Corporation","startDate":"2020-01-07","conditions":["Healthy"],"enrollment":32,"completionDate":"2020-04-20"},{"nctId":"NCT04231136","phase":"PHASE1","title":"Study to Evaluate the Pharmacodynamics After Single Oral Dosing of Tegoprazan, EAPA115 and RAPA115 in Healthy Volunteers","status":"COMPLETED","sponsor":"HK inno.N Corporation","startDate":"2020-01-14","conditions":["Healthy"],"enrollment":19,"completionDate":"2020-08-03"},{"nctId":"NCT04639804","phase":"PHASE1","title":"Pharmacokinetic Interaction Between Tegoprazan and NSAIDs After Multiple Oral Dosing in Healthy Male Volunteers","status":"COMPLETED","sponsor":"HK inno.N Corporation","startDate":"2020-06-06","conditions":["Healthy"],"enrollment":60,"completionDate":"2020-07-29"},{"nctId":"NCT04494269","phase":"PHASE1","title":"A Study to Evaluate Pharmacokinetics and Safety of Tegoprazan in Subjects With Hepatic Impairment and Healthy Controls","status":"UNKNOWN","sponsor":"HK inno.N Corporation","startDate":"2020-09-08","conditions":["Hepatic Impairment","Healthy"],"enrollment":28,"completionDate":"2023-12"},{"nctId":"NCT04171687","phase":"PHASE1","title":"Effect of Tegoprazan or RAPA113 on Pharmacodynamics/Pharmacokinetics of Clopidogrel in Healthy Male Volunteers","status":"COMPLETED","sponsor":"HK inno.N Corporation","startDate":"2019-10-21","conditions":["Healthy"],"enrollment":36,"completionDate":"2020-04-09"},{"nctId":"NCT03814642","phase":"PHASE1","title":"Effect of Tegoprazan on Pharmacodynamics of Clopidogrel in Healthy Male Participants","status":"COMPLETED","sponsor":"HK inno.N Corporation","startDate":"2019-01-21","conditions":["Healthy"],"enrollment":25,"completionDate":"2019-07-22"},{"nctId":"NCT04066257","phase":"PHASE1","title":"Evaluate the PK of Multiple Oral Doses of Tegoprazan, Metronidazole, Tetracycline and Bismuth in Healthy Volunteers","status":"COMPLETED","sponsor":"HK inno.N Corporation","startDate":"2019-01-17","conditions":["Healthy"],"enrollment":32,"completionDate":"2019-04-25"},{"nctId":"NCT03863938","phase":"PHASE1","title":"Food-Effect on PK and PD of Single Oral Dose of Tegoprazan in Healthy Male Subjects","status":"COMPLETED","sponsor":"HK inno.N Corporation","startDate":"2019-03-27","conditions":["Healthy"],"enrollment":12,"completionDate":"2019-06-25"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"chemblId":"CHEMBL216528"},"formularyStatus":[],"_enricherVersion":"v2-openfda","developmentCodes":[],"ownershipHistory":[{"period":"","companyName":"Wonkwang University Hospital","relationship":"Original Developer"}],"publicationCount":1,"therapeuticAreas":["Other"],"biosimilarFilings":[],"originalDeveloper":"Wonkwang University Hospital","recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"K-CAB","companyName":"Wonkwang University Hospital","companyId":"wonkwang-university-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"","enrichmentLevel":3,"visitCount":1,"regulatoryByCountry":[{"country_code":"CA","regulator":"Health Canada","status":"approved","approval_date":null,"mah":"","brand_name_local":"","application_number":""},{"country_code":"US","regulator":"FDA","status":"approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null}],"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T01:01:37.247127+00:00","fieldsConflicting":1,"overallConfidence":0.8},"verificationStatus":"enriching","dataCompleteness":{"mechanism":false,"indications":false,"safety":false,"trials":true,"score":1}}