{"id":"jiedu-huayu-oral-prescription","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This herbal oral prescription combines multiple botanical ingredients traditionally used in Chinese medicine to clear heat-toxins (jiedu) and invigorate blood circulation (huayu). The formulation is hypothesized to reduce hepatic inflammation, inhibit hepatic stellate cell activation, and promote resolution of fibrotic tissue remodeling in chronic liver disease. The mechanism reflects traditional Chinese medicine principles rather than a single molecular target.","oneSentence":"Jiedu Huayu Oral Prescription is a traditional Chinese medicine formulation designed to detoxify and resolve blood stasis, potentially improving hepatic fibrosis and cirrhosis outcomes.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:17:39.302Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hepatic fibrosis and cirrhosis (phase 3 development)"}]},"trialDetails":[{"nctId":"NCT07250035","phase":"PHASE3","title":"Jiedu Huayu Oral Prescription in the Treatment of Intracranial Hemorrhage Associated With Cerebral Amyloid Angiopathy","status":"NOT_YET_RECRUITING","sponsor":"Beijing Tiantan Hospital","startDate":"2025-12-20","conditions":"Cerebral Amyloid Angiopathy","enrollment":436}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Jiedu Huayu Oral Prescription","genericName":"Jiedu Huayu Oral Prescription","companyName":"Beijing Tiantan Hospital","companyId":"beijing-tiantan-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Jiedu Huayu Oral Prescription is a traditional Chinese medicine formulation designed to detoxify and resolve blood stasis, potentially improving hepatic fibrosis and cirrhosis outcomes. Used for Hepatic fibrosis and cirrhosis (phase 3 development).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}