{"id":"isotonic-nacl","safety":{"commonSideEffects":[{"rate":null,"effect":"Hyperchloremic acidosis (with prolonged high-volume use)"},{"rate":null,"effect":"Fluid overload / pulmonary edema (in susceptible patients)"},{"rate":null,"effect":"Hypernatremia (rare, with excessive administration)"}]},"_chembl":{"chemblId":"CHEMBL4438408","moleculeType":"Unknown","molecularWeight":"554.05"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Isotonic saline is a crystalloid solution with osmolarity matching blood plasma (~308 mOsm/L), allowing safe administration without causing cell lysis or crenation. It replaces lost fluids and maintains electrolyte homeostasis, particularly sodium and chloride ions. 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