{"id":"isotonic-0-3-sodium-hyaluronate","safety":{"commonSideEffects":[{"rate":null,"effect":"Transient blurred vision"},{"rate":null,"effect":"Eye irritation or discomfort"},{"rate":null,"effect":"Conjunctival hyperemia"}]},"_chembl":{"chemblId":"CHEMBL4594244","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Sodium hyaluronate is a high-molecular-weight polysaccharide that acts as a humectant and lubricant on the ocular surface. It binds water and forms a protective layer over the cornea and conjunctiva, reducing friction and promoting epithelial healing. This isotonic 0.3% formulation is designed for topical ophthalmic use to treat dry eye and related surface disorders.","oneSentence":"Sodium hyaluronate is a viscoelastic substance that lubricates and protects ocular surfaces by mimicking natural tear film components.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:17:21.302Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry eye syndrome / Keratoconjunctivitis sicca"},{"name":"Ocular surface protection and lubrication"}]},"trialDetails":[{"nctId":"NCT02777723","phase":"PHASE3","title":"Study to Evaluate the Efficacy and Safety of CKD-350","status":"UNKNOWN","sponsor":"Chong Kun Dang Pharmaceutical","startDate":"2016-05","conditions":"Dry Eye Syndrome","enrollment":138}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Arm B"],"phase":"phase_3","status":"active","brandName":"Isotonic 0.3% Sodium Hyaluronate","genericName":"Isotonic 0.3% Sodium Hyaluronate","companyName":"Chong Kun Dang Pharmaceutical","companyId":"chong-kun-dang-pharmaceutical","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Sodium hyaluronate is a viscoelastic substance that lubricates and protects ocular surfaces by mimicking natural tear film components. Used for Dry eye syndrome / Keratoconjunctivitis sicca, Ocular surface protection and lubrication.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}