{"id":"isopropanol","rwe":[],"_fda":{"id":"2778cad1-2929-fab8-e063-6294a90a2fc7","set_id":"aa0dc01a-2c6b-7402-e053-2a95a90af6a2","openfda":{"unii":["6DC9Q167V3"],"route":["TOPICAL"],"spl_id":["2778cad1-2929-fab8-e063-6294a90a2fc7"],"brand_name":["Instant Hand Sanitizeing Wipe"],"spl_set_id":["aa0dc01a-2c6b-7402-e053-2a95a90af6a2"],"package_ndc":["79539-002-01","79539-002-02","79539-002-03","79539-002-04","79539-002-05","79539-002-06","79539-002-07","79539-002-08","79539-002-09","79539-002-10","79539-002-11","79539-002-12","79539-002-13","79539-002-14","79539-002-15","79539-002-16","79539-002-17","79539-002-18","79539-002-19","79539-002-20","79539-002-21","79539-002-22","79539-002-23","79539-002-24"],"product_ndc":["79539-002"],"generic_name":["ISOPROPANOL AND COMPOUND DOUBLE-STRANDED QUATERNARY AMMONIUM SALTS"],"product_type":["HUMAN OTC DRUG"],"substance_name":["PROPYLENE GLYCOL"],"manufacturer_name":["Shandong Yayun Sanitary Products Co., Ltd."],"application_number":["M003"],"is_original_packager":[true]},"purpose":["Purpose Antiseptic, Instant Hand Sanitizeing Wipe"],"version":"6","stop_use":["Stop use and ask a doctor if irritation or rash occurs. These may be signs of a serious condition."],"warnings":["Warnings For external use only. Flammable. Keep away from heat or flame"],"do_not_use":["Do not use in children less than 2 months of age on open skin wounds"],"when_using":["When using this product keep out of eyes, ears, and mouth. In case of contact with eyes, rinse eyes thoroughly with water. Stop use and ask a doctor if irritation or rash occurs. These may be signs of a serious condition. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"effective_time":"20241121","active_ingredient":["Active Ingredient(s) BENZALKONIUM CHLORIDE 1.2g/pcs. Purpose: Antiseptic"],"inactive_ingredient":["Inactive ingredients WATER SODIUM CITRATE Compound double-stranded quaternary ammonium salt"],"storage_and_handling":["Other information Store between 15-30C (59-86F) Avoid freezing and excessive heat above 40C (104F)"],"indications_and_usage":["Use Instant Hand Sanitizeing Wipe to help reduce bacteria that potentially can cause disease. For use when soap and water are not available."],"spl_unclassified_section":["Instant Hand Sanitizeing Wipe"],"dosage_and_administration":["Directions Wipe the surface of the skin and let it dry naturally. Supervise children under 6 years of age when using this product to avoid swallowing."],"spl_product_data_elements":["Instant Hand Sanitizeing Wipe Isopropanol and Compound double-stranded quaternary ammonium salts GLYCERIN ALOE BARBADENSIS LEAF EXTRACT EDETATE DISODIUM PROPYLENE GLYCOL PROPYLENE GLYCOL PHENOXYETHANOL BENZALKONIUM CHLORIDE WATER .ALPHA.-TOCOPHEROL ACETATE CETYLPYRIDINIUM CHLORIDE SULFURYL FLUORIDE SODIUM CITRATE CHAMOMILE"],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"package_label_principal_display_panel":["Package Label - Principal Display Panel 2"]},"tags":[{"label":"isopropanol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"D08AX05","category":"atc"},{"label":"Cutaneous","category":"route"},{"label":"Extracorporeal","category":"route"},{"label":"Topical","category":"route"},{"label":"Aerosol","category":"form"},{"label":"Cloth","category":"form"},{"label":"Active","category":"status"},{"label":"Antiseptic preparation","category":"indication"},{"label":"Solvents","category":"pharmacology"}],"phase":"marketed","safety":{"boxedWarnings":[],"safetySignals":[{"llr":9402.898,"date":"","count":4170,"signal":"Completed suicide","source":"DrugCentral FAERS","actionTaken":"Reported 4,170 times (LLR=9403)"},{"llr":7588.384,"date":"","count":3232,"signal":"Drug abuse","source":"DrugCentral FAERS","actionTaken":"Reported 3,232 times (LLR=7588)"},{"llr":6990.935,"date":"","count":4240,"signal":"Toxicity to various agents","source":"DrugCentral FAERS","actionTaken":"Reported 4,240 times (LLR=6991)"},{"llr":1891.88,"date":"","count":1140,"signal":"Intentional overdose","source":"DrugCentral FAERS","actionTaken":"Reported 1,140 times (LLR=1892)"},{"llr":1758.445,"date":"","count":1070,"signal":"Cardio-respiratory arrest","source":"DrugCentral FAERS","actionTaken":"Reported 1,070 times (LLR=1758)"},{"llr":1368.176,"date":"","count":1189,"signal":"Overdose","source":"DrugCentral FAERS","actionTaken":"Reported 1,189 times (LLR=1368)"},{"llr":1136.19,"date":"","count":772,"signal":"Suicide attempt","source":"DrugCentral FAERS","actionTaken":"Reported 772 times (LLR=1136)"},{"llr":1050.962,"date":"","count":309,"signal":"Alcohol interaction","source":"DrugCentral FAERS","actionTaken":"Reported 309 times (LLR=1051)"},{"llr":851.271,"date":"","count":323,"signal":"Suspected suicide","source":"DrugCentral FAERS","actionTaken":"Reported 323 times (LLR=851)"},{"llr":801.347,"date":"","count":267,"signal":"Alcohol abuse","source":"DrugCentral FAERS","actionTaken":"Reported 267 times (LLR=801)"},{"llr":787.559,"date":"","count":634,"signal":"Intentional product misuse","source":"DrugCentral FAERS","actionTaken":"Reported 634 times (LLR=788)"},{"llr":630.294,"date":"","count":212,"signal":"Alcohol poisoning","source":"DrugCentral FAERS","actionTaken":"Reported 212 times (LLR=630)"},{"llr":469.198,"date":"","count":369,"signal":"Respiratory arrest","source":"DrugCentral FAERS","actionTaken":"Reported 369 times (LLR=469)"},{"llr":429.312,"date":"","count":179,"signal":"Exposure to toxic agent","source":"DrugCentral FAERS","actionTaken":"Reported 179 times (LLR=429)"},{"llr":418.523,"date":"","count":317,"signal":"Drug dependence","source":"DrugCentral FAERS","actionTaken":"Reported 317 times (LLR=419)"}],"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[{"source":"FDA Orange Book via DrugCentral","expires":"2036-04-24","territory":"US","patentNumber":"9844654"},{"source":"FDA Orange Book via DrugCentral","expires":"2034-12-20","territory":"US","patentNumber":"10688291"},{"source":"FDA Orange Book via DrugCentral","expires":"2029-08-09","territory":"US","patentNumber":"8389583"},{"source":"FDA Orange Book via DrugCentral","expires":"2028-05-23","territory":"US","patentNumber":"8703828"},{"source":"FDA Orange Book via DrugCentral","expires":"2028-05-23","territory":"US","patentNumber":"9629368"},{"source":"FDA Orange Book via DrugCentral","expires":"2027-04-25","territory":"US","patentNumber":"7422388"},{"source":"FDA Orange Book via DrugCentral","expires":"2025-05-06","territory":"US","patentNumber":"8226971"},{"source":"FDA Orange Book via DrugCentral","expires":"2025-02-08","territory":"US","patentNumber":"9011897"},{"source":"FDA Orange Book via DrugCentral","expires":"2024-01-31","territory":"US","patentNumber":"6991394"},{"source":"FDA Orange Book via DrugCentral","expires":"2023-12-30","territory":"US","patentNumber":"7182536"},{"source":"FDA Orange Book via DrugCentral","expires":"2023-03-14","territory":"US","patentNumber":"6729786"},{"source":"FDA Orange Book via DrugCentral","expires":"2023-03-14","territory":"US","patentNumber":"7241065"}],"pricing":[],"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=isopropanol","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T01:03:41.642351+00:00"},"patents":{"url":"","method":"deterministic","source":"FDA Orange Book","rawText":"","confidence":1,"sourceType":"fda_orange_book","retrievedAt":"2026-04-20T01:03:41.642244+00:00"},"timeline":{"url":"https://en.wikipedia.org/wiki/Isopropanol","method":"deterministic","source":"Wikipedia","rawText":"","confidence":0.8,"sourceType":"wikipedia","retrievedAt":"2026-04-20T01:03:48.360037+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T01:03:46.961493+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=isopropanol","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T01:03:47.302335+00:00"},"administration.route":{"url":"","method":"deterministic","source":"FDA Label","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T01:03:39.541828+00:00"},"safety.boxedWarnings":{"url":"","method":"deterministic","source":"FDA Label (no boxed warning)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T01:03:39.541844+00:00"},"crossReferences.chemblId":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL1956007/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-20T01:03:48.008232+00:00"},"regulatory.fda_application":{"url":"","method":"deterministic","source":"FDA Label","rawText":"M003","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T01:03:39.541848+00:00"}},"allNames":"zuragard","offLabel":[],"synonyms":["isopropyl alcohol","2-Propanol","iso-Propanol","isopropanol"],"timeline":[],"approvals":[{"date":"","orphan":false,"company":"","regulator":"FDA"}],"brandName":"Zuragard","ecosystem":[{"indication":"Antiseptic preparation","otherDrugs":[{"name":"boric acid","slug":"boric-acid","company":""},{"name":"chloroxylenol","slug":"chloroxylenol","company":""},{"name":"ethanol","slug":"ethanol","company":"B Braun"},{"name":"hydrogen peroxide","slug":"hydrogen-peroxide","company":""}],"globalPrevalence":null}],"mechanism":{"novelty":"First-in-class","modality":"Small Molecule","drugClass":"isopropanol","explanation":"","oneSentence":"","technicalDetail":"Isopropanol exerts its antimicrobial effects by disrupting the cell membrane of microorganisms, leading to the loss of cellular integrity and ultimately cell death. This is achieved through the denaturation of proteins and the disruption of the cell membrane's lipid bilayer, making it difficult for the microorganism to maintain its structural and functional integrity."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Isopropyl_alcohol","title":"Isopropyl alcohol","extract":"Isopropyl alcohol is a colorless, flammable, organic compound with a pungent odor.","wiki_history":"== History ==\nIsopropyl alcohol was first synthesized by the chemist Alexander William Williamson in 1853. He achieved this by heating a mixture of propene and sulfuric acid.\nStandard Oil produced isopropyl alcohol by hydrating propene. Isopropyl alcohol was oxidized to acetone for the preparation of cordite, a smokeless, low explosive propellant."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4215","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=isopropanol","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=isopropanol","fields":["publications"],"source":"PubMed/NCBI"},{"id":4,"url":"https://en.wikipedia.org/wiki/Isopropyl_alcohol","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T14:01:22.771697","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T01:03:50.384158+00:00","fieldsConflicting":2,"overallConfidence":0.8},"biosimilars":[],"competitors":[{"drugName":"hydrogen peroxide","drugSlug":"hydrogen-peroxide","fdaApproval":"","patentExpiry":"Jul 4, 2035","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"tosylchloramide sodium","drugSlug":"tosylchloramide-sodium","fdaApproval":"","relationship":"same-class"},{"drugName":"sodium hypochlorite","drugSlug":"sodium-hypochlorite","fdaApproval":"","relationship":"same-class"},{"drugName":"ethanol","drugSlug":"ethanol","fdaApproval":"1946-01-17","patentStatus":"Unknown","relationship":"same-class"}],"genericName":"isopropanol","indications":{"approved":[{"name":"Antiseptic preparation","source":"DrugCentral","snomedId":261276004,"regulator":"FDA","eligibility":"all ages, no specific eligibility criteria mentioned"}],"offLabel":[{"name":"Nausea and vomiting","source":"DrugCentral","drugName":"isopropanol","evidenceCount":32,"evidenceLevel":"moderate"}],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"hydrogen-peroxide","brandName":"hydrogen peroxide","genericName":"hydrogen peroxide","approvalYear":"","relationship":"same-class"},{"drugId":"tosylchloramide-sodium","brandName":"tosylchloramide sodium","genericName":"tosylchloramide sodium","approvalYear":"","relationship":"same-class"},{"drugId":"sodium-hypochlorite","brandName":"sodium hypochlorite","genericName":"sodium hypochlorite","approvalYear":"","relationship":"same-class"},{"drugId":"ethanol","brandName":"ethanol","genericName":"ethanol","approvalYear":"1946","relationship":"same-class"}],"trialDetails":[{"nctId":"NCT05828810","phase":"NA","title":"CLinical Evaluation of ANtiseptic Skin Preparation in Revision Total Joint Arthroplasty of the Hip and Knee","status":"RECRUITING","sponsor":"Sunnybrook Health Sciences Centre","startDate":"2023-07-25","conditions":["Revision Total Hip Arthroplasty (RTHA)","Revision Total Knee Arthroplasty"],"enrollment":400,"completionDate":"2026-11"},{"nctId":"NCT06967129","phase":"NA","title":"Evaluation of Daily Disposable Toric Soft Lenses Manufactured With an Alternative Hydration Process","status":"COMPLETED","sponsor":"Johnson & Johnson Vision Care, Inc.","startDate":"2025-04-25","conditions":["Astigmatism"],"enrollment":281,"completionDate":"2025-07-14"},{"nctId":"NCT03728335","phase":"PHASE2","title":"Enasidenib (AG-221) Maintenance Post Allogeneic HCT in Patients With IDH2 Mutation","status":"RECRUITING","sponsor":"City of Hope Medical Center","startDate":"2019-07-11","conditions":["Acute Myeloid Leukemia"],"enrollment":35,"completionDate":"2027-01-11"},{"nctId":"NCT05497583","phase":"NA","title":"HEMA-free Universal Adhesives for Restoring Non-carious Cervical Lesions","status":"COMPLETED","sponsor":"Cairo University","startDate":"2023-01-15","conditions":["Universal Adhesive"],"enrollment":28,"completionDate":"2024-11-23"},{"nctId":"NCT03683433","phase":"PHASE2","title":"Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation","status":"RECRUITING","sponsor":"M.D. Anderson Cancer Center","startDate":"2018-09-18","conditions":["Acute Bilineal Leukemia","Acute Biphenotypic Leukemia","Chronic Myelomonocytic Leukemia","IDH2 Gene Mutation","Myelodysplastic Syndrome","Recurrent Acute Myeloid Leukemia","Refractory Acute Myeloid Leukemia"],"enrollment":50,"completionDate":"2027-09-20"},{"nctId":"NCT07408921","phase":"NA","title":"Effect of Ice Pack and Warm Gel Pad Use During Drain Removal on Anxiety, Comfort, Physiological Parameters, and Patient Satisfaction Undergoing Open Urological Surgery","status":"RECRUITING","sponsor":"Tarsus University","startDate":"2026-02-15","conditions":["Drain"],"enrollment":120,"completionDate":"2026-12-15"},{"nctId":"NCT03885791","phase":"NA","title":"Randomized Controlled Trial of Vaginal Cryotherapy for Pelvic Floor Myofascial Pain","status":"COMPLETED","sponsor":"Washington University School of Medicine","startDate":"2019-03-22","conditions":["Pelvic Floor Myofascial Pain","Pelvic Pain","Myofascial Pain"],"enrollment":165,"completionDate":"2024-07-24"},{"nctId":"NCT06533345","phase":"NA","title":"VCOM Pain Free Research Collaborative","status":"RECRUITING","sponsor":"Edward Via Virginia College of Osteopathic Medicine","startDate":"2024-08-30","conditions":["Chronic Pain"],"enrollment":120,"completionDate":"2027-08-01"},{"nctId":"NCT05741164","phase":"PHASE2","title":"Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory Metastatic or Unresectable Triple Negative Breast Cancer","status":"NOT_YET_RECRUITING","sponsor":"Emory University","startDate":"2026-03-30","conditions":["Anatomic Stage III Breast Cancer AJCC v8","Anatomic Stage IV Breast Cancer AJCC v8","Metastatic Triple-Negative Breast Carcinoma","Refractory Triple-Negative Breast Carcinoma","Unresectable Triple-Negative Breast Carcinoma"],"enrollment":37,"completionDate":"2028-11-30"},{"nctId":"NCT06865170","phase":"PHASE4","title":"Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?","status":"NOT_YET_RECRUITING","sponsor":"University of California, Davis","startDate":"2026-05","conditions":["Osteoarthritis (OA) of the Knee","Fear of Needles"],"enrollment":88,"completionDate":"2026-05"},{"nctId":"NCT04203316","phase":"PHASE2","title":"Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With an IDH2 Mutation","status":"ACTIVE_NOT_RECRUITING","sponsor":"Children's Oncology Group","startDate":"2023-08-14","conditions":["Recurrent Acute Myeloid Leukemia","Refractory Acute Myeloid Leukemia"],"enrollment":1,"completionDate":"2026-10-03"},{"nctId":"NCT05920122","phase":"PHASE4","title":"Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections","status":"COMPLETED","sponsor":"Hyagriv Simhan","startDate":"2023-10-09","conditions":["Surgical Site Infection","Cesarean Section; Infection"],"enrollment":1398,"completionDate":"2025-10-17"},{"nctId":"NCT05080764","phase":"PHASE2","title":"Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Moderate to Severe Acne Vulgaris With Photodynamic Therapy in Adults","status":"ACTIVE_NOT_RECRUITING","sponsor":"Biofrontera Inc.","startDate":"2021-12-10","conditions":["Acne Vulgaris"],"enrollment":126,"completionDate":"2026-01"},{"nctId":"NCT07287722","phase":"NA","title":"Soft Tissue Response and IL-1β Levels Around CAD/CAM-Milled vs 3D-Printed PMMA Healing Abutments","status":"ACTIVE_NOT_RECRUITING","sponsor":"Ali Hassan Eid Toto","startDate":"2025-11-23","conditions":["Peri-implant Soft Tissue Healing"],"enrollment":22,"completionDate":"2025-12-23"},{"nctId":"NCT01366417","phase":"PHASE4","title":"Topical Antimicrobial Effectiveness Testing","status":"COMPLETED","sponsor":"C. R. Bard","startDate":"2011-05","conditions":["Antimicrobial Effectiveness"],"enrollment":25,"completionDate":"2011-06"},{"nctId":"NCT01314703","phase":"PHASE4","title":"Topical Antimicrobial Effectiveness Testing","status":"COMPLETED","sponsor":"C. R. Bard","startDate":"2011-03","conditions":["Antimicrobial Effectiveness"],"enrollment":27,"completionDate":"2011-04"},{"nctId":"NCT00799812","phase":"PHASE3","title":"Test for Pre Operative Skin Preparations","status":"COMPLETED","sponsor":"C. R. Bard","startDate":"2007-11-13","conditions":["Topical Antisepsis"],"enrollment":335,"completionDate":"2008-06-19"},{"nctId":"NCT05312255","phase":"NA","title":"Non-chemotherapeutic Interventions for the Improvement of Quality of Life and Immune Function in Patients With Multiple Myeloma","status":"RECRUITING","sponsor":"Roswell Park Cancer Institute","startDate":"2022-06-28","conditions":["Plasma Cell Myeloma","Recurrent Plasma Cell Myeloma","Refractory Plasma Cell Myeloma","Smoldering Plasma Cell Myeloma"],"enrollment":175,"completionDate":"2027-06-28"},{"nctId":"NCT00636480","phase":"PHASE3","title":"Preoperative Skin Preparation Evaluation","status":"COMPLETED","sponsor":"C. R. Bard","startDate":"2007-10","conditions":["Topical Antisepsis"],"enrollment":60,"completionDate":"2008-03"},{"nctId":"NCT04181463","phase":"PHASE2","title":"Nasal Inhalation of Isopropyl Alcohol for the Treatment of Nausea in Patients With Cancer","status":"NOT_YET_RECRUITING","sponsor":"M.D. Anderson Cancer Center","startDate":"2025-11-05","conditions":["Malignant Neoplasm"],"enrollment":112,"completionDate":"2025-12-30"},{"nctId":"NCT05175521","phase":"NA","title":"Inhaled IAV vs Inhaled Eucalyptus for the Treatment of Nausea With Acute Migraine","status":"ACTIVE_NOT_RECRUITING","sponsor":"HonorHealth Research Institute","startDate":"2021-11-11","conditions":["Migraine"],"enrollment":50,"completionDate":"2026-01-31"},{"nctId":"NCT06833320","phase":"PHASE1,PHASE2","title":"Propranolol Treatment for Postoperative Chylothorax","status":"RECRUITING","sponsor":"June Wu","startDate":"2025-09-09","conditions":["Postoperative Chylothorax","Congenital Heart Disease","Open Heart Surgery","Chylothorax"],"enrollment":50,"completionDate":"2031-01-01"},{"nctId":"NCT05418244","phase":"PHASE2,PHASE3","title":"Inhaled Isopropyl Alcohol for Treatment of Nausea","status":"RECRUITING","sponsor":"State University of New York at Buffalo","startDate":"2022-04-20","conditions":["Vomiting","Nausea","Children, Only"],"enrollment":84,"completionDate":"2026-06-30"},{"nctId":"NCT05441514","phase":"PHASE1","title":"Enasidenib in Combination With Cobimetinib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia","status":"ACTIVE_NOT_RECRUITING","sponsor":"City of Hope Medical Center","startDate":"2022-11-03","conditions":["Recurrent Acute Myeloid Leukemia","Refractory Acute Myeloid Leukemia"],"enrollment":3,"completionDate":"2027-05-03"},{"nctId":"NCT06900413","phase":"NA","title":"ESP vs. EXORA Blocks for Analgesia in Laparoscopic Cholecystectomy","status":"NOT_YET_RECRUITING","sponsor":"Aycan KURTARANGİL DOĞAN","startDate":"2025-09","conditions":["Erector Spinae Plane Block","Laparoscopic Cholecystectomy","Plane Block"],"enrollment":56,"completionDate":"2026-03"},{"nctId":"NCT06958276","phase":"NA","title":"Effect of US-Guided PNM in CrossFit With Nonspecific Shoulder Pain","status":"COMPLETED","sponsor":"Universidad de Zaragoza","startDate":"2025-05-01","conditions":["Nonspecific Shoulder Pain","Shoulder Pain Syndrome"],"enrollment":42,"completionDate":"2025-07-31"},{"nctId":"NCT06670976","phase":"PHASE1","title":"Propranolol Plus Standard Radiation Therapy Before Surgery for the Treatment of Patients With Soft Tissue Sarcoma","status":"WITHDRAWN","sponsor":"Roswell Park Cancer Institute","startDate":"2026-05-15","conditions":["Soft Tissue Sarcoma"],"enrollment":0,"completionDate":"2029-11-15"},{"nctId":"NCT06733506","phase":"PHASE4","title":"A Pilot Study to Evaluate Skin Swabbing With Chlorhexidine to Prevent Skin And Soft Tissue Infections Among People Who Inject Drugs","status":"COMPLETED","sponsor":"Gabriel John Culbert","startDate":"2018-10-01","conditions":["Opioid Use Disorder","Injection Drug Use","Skin and Soft Tissue Infections (SSTIs)"],"enrollment":56,"completionDate":"2019-05-01"},{"nctId":"NCT06929923","phase":"NA","title":"Pro-2-Cool Pivotal Trial II","status":"SUSPENDED","sponsor":"TecTraum Inc.","startDate":"2025-02-20","conditions":["Mild Traumatic Brain Injury"],"enrollment":72,"completionDate":"2026-02"},{"nctId":"NCT07009197","phase":"NA","title":"Effect of Instrument Assisted Soft Tissue Mobilization on Hand Post Surgical Scars in Primary Flexor Tendons Repair in Zone v","status":"NOT_YET_RECRUITING","sponsor":"Cairo University","startDate":"2025-06-05","conditions":["Hand Injuries"],"enrollment":42,"completionDate":"2025-09-01"},{"nctId":"NCT05937412","phase":"NA","title":"A Comparative Study Between Honey and Alcohol as Topical Skin Disinfectant","status":"RECRUITING","sponsor":"Ain Shams University","startDate":"2023-08-30","conditions":["Disinfectant Causing Toxic Effect"],"enrollment":70,"completionDate":"2025-08-28"},{"nctId":"NCT05401292","phase":"PHASE4","title":"Skin Preparation for Elective Foot and Ankle Surgery","status":"RECRUITING","sponsor":"University of Missouri-Columbia","startDate":"2022-02-15","conditions":["Microbial Colonization","Foot and Ankle Disorders"],"enrollment":100,"completionDate":"2025-12"},{"nctId":"NCT04307550","phase":"NA","title":"Inhaled Isopropyl Alcohol Versus Placebo to Manage Nausea at Electronic Dance Music Festivals","status":"COMPLETED","sponsor":"Anthony Seto","startDate":"2021-07-12","conditions":["Nausea"],"enrollment":55,"completionDate":"2024-10-27"},{"nctId":"NCT04534348","phase":"","title":"Study on the Reduction of Catheter-related Infections by Use of Self-disinfecting Venous and Arterial Access Caps","status":"COMPLETED","sponsor":"University of Cologne","startDate":"2017-11-01","conditions":["CLABSI - Central Line Associated Bloodstream Infection","Catheter-Related Blood Stream Infection"],"enrollment":598,"completionDate":"2020-01-31"},{"nctId":"NCT04879524","phase":"","title":"Infracoccygeal Botox for Dyssynergia","status":"COMPLETED","sponsor":"Queen Mary University of London","startDate":"2021-08-06","conditions":["Dyssynergic Defaecation","Evacuation Disorder","Anismus","Defecation Disorder"],"enrollment":8,"completionDate":"2022-12-20"},{"nctId":"NCT06836271","phase":"PHASE2","title":"Cleaning the Biopsy Needle in TRUS Bx","status":"NOT_YET_RECRUITING","sponsor":"Hitit University","startDate":"2025-03-01","conditions":["Prostatic Cancer"],"enrollment":200,"completionDate":"2025-06-30"},{"nctId":"NCT06729255","phase":"PHASE4","title":"A Prospective Cohort Study to Evaluate the Safety, Efficacy, and Usability of the EpiZact Device","status":"NOT_YET_RECRUITING","sponsor":"Oregon Health and Science University","startDate":"2025-03-15","conditions":["Postdural Puncture Headache","Epidural Analgesia, Obstetric"],"enrollment":100,"completionDate":"2026-12-31"},{"nctId":"NCT05919888","phase":"PHASE4","title":"SURGX Antimicrobial Gel Versus Povidone-iodine Skin Incision Prep in Total Shoulder Arthroplasty","status":"COMPLETED","sponsor":"St. Louis University","startDate":"2023-06-26","conditions":["Surgery","Surgical Site Infection","Cutibacterium Acnes","Prosthetic-joint Infection"],"enrollment":60,"completionDate":"2023-11-14"},{"nctId":"NCT03523962","phase":"PHASE4","title":"Pre-operative Alcohol Skin Solutions in Fractured Extremities","status":"COMPLETED","sponsor":"University of Maryland, Baltimore","startDate":"2018-08-21","conditions":["Surgical Site Infection","Unplanned Fracture-Related Reoperation","Open Appendicular Fracture","Closed Lower Extremity Fracture","Pelvic Fracture"],"enrollment":8485,"completionDate":"2024-02-02"},{"nctId":"NCT01968356","phase":"PHASE3","title":"In-vivo Efficacy Study of Patient Preoperative Preps","status":"TERMINATED","sponsor":"Solventum US LLC","startDate":"2013-10","conditions":["Skin Flora Bacterial Reduction Post-product Application"],"enrollment":171,"completionDate":"2014-01"},{"nctId":"NCT01968707","phase":"PHASE3","title":"In-vivo Efficacy Study of Patient Pre-operative Preps","status":"COMPLETED","sponsor":"Solventum US LLC","startDate":"2013-10","conditions":["Bacterial Reduction on Skin Flora Post-product Application"],"enrollment":426,"completionDate":"2014-06"},{"nctId":"NCT02447497","phase":"PHASE2","title":"In Vivo Patient Preoperative Skin Prep Persistence","status":"COMPLETED","sponsor":"Solventum US LLC","startDate":"2015-03","conditions":["Bacterial Recovery of Skin Flora Post-Product Application"],"enrollment":27,"completionDate":"2015-04"},{"nctId":"NCT03681990","phase":"PHASE2","title":"In Vivo Preoperative Skin Preparation Efficacy Study Within a Defined Product Coverage Area","status":"COMPLETED","sponsor":"Solventum US LLC","startDate":"2017-06-06","conditions":["Surgical Skin Preparation","Surgical Procedure, Unspecified"],"enrollment":28,"completionDate":"2017-07-04"},{"nctId":"NCT03155178","phase":"PHASE2","title":"In Vivo Preoperative Skin Preparation Persistence Evaluation","status":"COMPLETED","sponsor":"Solventum US LLC","startDate":"2016-12-05","conditions":["Bacterial Recovery of Skin Flora Post-product Application"],"enrollment":69,"completionDate":"2017-04-25"},{"nctId":"NCT06194903","phase":"NA","title":"Randomized Pilot Study Evaluating Isopropyl Alcohol and UVC Rays in Disinfection of Cell Phones","status":"COMPLETED","sponsor":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","startDate":"2024-02-01","conditions":["Cross Infection"],"enrollment":72,"completionDate":"2024-04-01"},{"nctId":"NCT06365528","phase":"NA","title":"Tunneled Peripherally Inserted Central Catheter (PICC) in Adult Patients and Associated Outcomes","status":"RECRUITING","sponsor":"Hospital de Clinicas de Porto Alegre","startDate":"2024-05-06","conditions":["CLABSI - Central Line Associated Bloodstream Infection","Deep Vein Thrombosis","Dislodged Catheter","Occlusion","Catheter Rupture","Catheter (Other); Complications"],"enrollment":840,"completionDate":"2026-07-31"},{"nctId":"NCT04756804","phase":"PHASE3","title":"Perioperative Patient Skin Antiseptic Preparation Evaluation","status":"COMPLETED","sponsor":"Zurex Pharma, Inc.","startDate":"2021-06-21","conditions":["Surgical Site Infection"],"enrollment":51,"completionDate":"2022-09-29"},{"nctId":"NCT06312605","phase":"PHASE4","title":"The Adjunctive Role of Vitamin C on Pigment Recurrence (Randomized Clinical and Histological Trial)","status":"RECRUITING","sponsor":"Ain Shams University","startDate":"2023-08-01","conditions":["Gingival Pigmentation"],"enrollment":24,"completionDate":"2024-08"},{"nctId":"NCT06077032","phase":"NA","title":"Chlorhexidine and Garlic Extract as Potential Topical Virucidal Therapeutic Agents of Non-Genital Warts","status":"UNKNOWN","sponsor":"Assiut University","startDate":"2023-11-01","conditions":["Non-Genital Warts"],"enrollment":90,"completionDate":"2025-12-01"},{"nctId":"NCT03825796","phase":"PHASE2","title":"CPX-351 Plus Enasidenib for Relapsed AML","status":"ACTIVE_NOT_RECRUITING","sponsor":"Jonsson Comprehensive Cancer Center","startDate":"2019-04-12","conditions":["Recurrent Acute Myeloid Leukemia"],"enrollment":2,"completionDate":"2024-09-01"},{"nctId":"NCT03125811","phase":"EARLY_PHASE1","title":"Value of Ondansetron Medication vs Inhaled Isopropyl Therapy in the Emergency Department (VOMIITED)","status":"COMPLETED","sponsor":"Texas Tech University Health Sciences Center, El Paso","startDate":"2017-07-17","conditions":["Nausea","Vomiting"],"enrollment":121,"completionDate":"2023-03-01"},{"nctId":"NCT04885491","phase":"PHASE1,PHASE2","title":"A Study to Evaluate the Efficacy, Safety and Tolerability of PDNO Infusion in COVID-19 Patients With Acute Pulmonary Hypertension","status":"WITHDRAWN","sponsor":"Attgeno AB","startDate":"2021-05-07","conditions":["Pulmonary Hypertension","COVID-19"],"enrollment":0,"completionDate":"2023-04-30"},{"nctId":"NCT05699486","phase":"PHASE2","title":"A Study to Evaluate the Efficacy, Safety and Tolerability of PDNO Infusion in Patients With Pulmonary Hypertension After Cardiopulmonary Bypass Surgery","status":"UNKNOWN","sponsor":"Attgeno AB","startDate":"2022-10-23","conditions":["Pulmonary Hypertension"],"enrollment":12,"completionDate":"2023-12-31"},{"nctId":"NCT03859908","phase":"PHASE4","title":"Comparison of Two Preoperative Antiseptic Solutions Alcohol Based in Abdominal Elective Surgeries","status":"TERMINATED","sponsor":"Universidad de El Salvador","startDate":"2019-04-05","conditions":["Surgical Site Infection"],"enrollment":18,"completionDate":"2021-01-27"},{"nctId":"NCT03782103","phase":"PHASE3","title":"In-vivo Efficacy of Patient Preoperative Prep, ZuraPrep (ZP)","status":"COMPLETED","sponsor":"Zurex Pharma, Inc.","startDate":"2019-01-25","conditions":["Surgical Skin Preparation"],"enrollment":156,"completionDate":"2019-09-26"},{"nctId":"NCT02831998","phase":"PHASE3","title":"In-vivo Efficacy of Patient Preoperative Prep","status":"COMPLETED","sponsor":"Zurex Pharma, Inc.","startDate":"2016-07-27","conditions":["Surgical Skin Preparation"],"enrollment":440,"completionDate":"2017-04-09"},{"nctId":"NCT05705895","phase":"NA","title":"The Efficiency of the Central Venous Catheter Care Protocol","status":"UNKNOWN","sponsor":"Saglik Bilimleri Universitesi Gulhane Tip Fakultesi","startDate":"2022-01-01","conditions":["Stem Cell Transplant Complications","Central Venous Catheter Exit Site Infection"],"enrollment":60,"completionDate":"2023-12-01"},{"nctId":"NCT04891354","phase":"PHASE1","title":"A First-in-Human Study to Assess the Safety and Tolerability of PDNO","status":"COMPLETED","sponsor":"Attgeno AB","startDate":"2021-02-02","conditions":["Pulmonary Hypertension"],"enrollment":38,"completionDate":"2022-05-25"},{"nctId":"NCT05664165","phase":"NA","title":"The Efficiency of Dry Needling and Cold Spray-stretching Treatments","status":"COMPLETED","sponsor":"Haydarpasa Numune Training and Research Hospital","startDate":"2019-05-25","conditions":["Myofascial Pain Syndromes","Myofascial Trigger Point Pain"],"enrollment":60,"completionDate":"2019-09-30"},{"nctId":"NCT03838575","phase":"PHASE3","title":"ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions","status":"UNKNOWN","sponsor":"University of Birmingham","startDate":"2019-03-01","conditions":["Surgical Site Infection","Surgical Wound Infection","Surgery--Complications","Surgery"],"enrollment":6610,"completionDate":"2023-08"},{"nctId":"NCT04464915","phase":"NA","title":"Isopropyl Alcohol Inhalation as Anti-emetic Therapy in the Emergency Department","status":"WITHDRAWN","sponsor":"Ottawa Hospital Research Institute","startDate":"2020-07","conditions":["Nausea","Vomiting"],"enrollment":0,"completionDate":"2020-11"},{"nctId":"NCT04929535","phase":"PHASE2","title":"Hydrogen Peroxide Trial to Investigate the Efficacy of 30%H2O2 as a Topical Application Before Definitive Treatment","status":"UNKNOWN","sponsor":"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","startDate":"2022-09","conditions":["Basal Cell Carcinoma","Squamous Cell Carcinoma of Skin Differentiated"],"enrollment":51,"completionDate":"2023-12"},{"nctId":"NCT02202577","phase":"NA","title":"Chlorhexidine-Alcohol Versus Povidone-Iodine for Cesarean Antisepsis","status":"COMPLETED","sponsor":"Case Western Reserve University","startDate":"2014-03","conditions":["Surgical Site Infection"],"enrollment":932,"completionDate":"2016-07"},{"nctId":"NCT03560193","phase":"PHASE4","title":"Randomized Trial of 2% Chlorhexidine-70% Isopropanol vs 5% Povidone Iodine-69% Ethanol for Skin Antisepsis in Reducing Surgical-site Infection After Cardiac Surgery","status":"COMPLETED","sponsor":"Poitiers University Hospital","startDate":"2018-09-10","conditions":["Cardiac Surgery in Adult Patient"],"enrollment":3316,"completionDate":"2022-05-25"},{"nctId":"NCT04655391","phase":"PHASE1","title":"Glasdegib-Based Treatment Combinations for the Treatment of Patients With Relapsed Acute Myeloid Leukemia Who Have Undergone Hematopoietic Cell Transplantation","status":"WITHDRAWN","sponsor":"City of Hope Medical Center","startDate":"2022-06-25","conditions":["Recurrent Acute Myeloid Leukemia"],"enrollment":0,"completionDate":"2023-12-15"},{"nctId":"NCT04300010","phase":"PHASE4","title":"Blue Light Therapy of C. Acnes","status":"COMPLETED","sponsor":"University of Wisconsin, Madison","startDate":"2020-10-05","conditions":["Acne"],"enrollment":60,"completionDate":"2021-01-22"},{"nctId":"NCT03861780","phase":"PHASE3","title":"Pilot Evaluation of Two Test Materials With a Positive Control When Used as a Patient Preoperative Skin Preparation","status":"COMPLETED","sponsor":"Professional Disposables International, Inc.","startDate":"2019-04-02","conditions":["Bacteria Microflora Reduction"],"enrollment":152,"completionDate":"2019-06-06"},{"nctId":"NCT04218110","phase":"PHASE3","title":"Preoperative Skin Preparation Study to Evaluate the Antimicrobial Capabilities of Four Test Substances","status":"COMPLETED","sponsor":"Professional Disposables International, Inc.","startDate":"2020-02-11","conditions":["Surgical Site Infection"],"enrollment":329,"completionDate":"2020-03-31"},{"nctId":"NCT03817580","phase":"PHASE3","title":"Comparative Study of Antimicrobial Effectiveness","status":"COMPLETED","sponsor":"Professional Disposables International, Inc.","startDate":"2019-02-18","conditions":["Bacterial Microflora Reduction"],"enrollment":170,"completionDate":"2019-06-04"},{"nctId":"NCT02479347","phase":"PHASE4","title":"Wound Infections in Breast Cancer Surgery After Preoperative Skin Preparation With Chlorhexidine vs. Povidone-iodine","status":"COMPLETED","sponsor":"Fondazione IRCCS Istituto Nazionale dei Tumori, Milano","startDate":"2013-03","conditions":["Wound Infection","Breast Neoplasms"],"enrollment":2158,"completionDate":"2016-09"},{"nctId":"NCT03694613","phase":"NA","title":"Utility of Placental/Umbilical Cord Blood in Early Onset Neonatal Sepsis in Very Low Birth Weight Infants","status":"COMPLETED","sponsor":"The University of Texas Medical Branch, Galveston","startDate":"2019-06-01","conditions":["Preterm Infant","Early-Onset Neonatal Sepsis","Umbilical Cord"],"enrollment":65,"completionDate":"2020-08-20"},{"nctId":"NCT04985526","phase":"NA","title":"Skin Microbiome and Polymorphic Light Eruption","status":"UNKNOWN","sponsor":"Medical University of Graz","startDate":"2021-05-07","conditions":["Polymorphic Light Eruption"],"enrollment":30,"completionDate":"2023-06-30"},{"nctId":"NCT04971317","phase":"NA","title":"The Influence of Simple, Low-Cost Chemistry Intervention Videos: A Randomized Trial of Children's Preferences for Sugar-Sweetened Beverages","status":"COMPLETED","sponsor":"NYU Langone Health","startDate":"2018-09-05","conditions":["Obesity","Type 2 Diabetes","Dental Caries"],"enrollment":326,"completionDate":"2018-12-30"},{"nctId":"NCT02831816","phase":"PHASE3","title":"Clinical Evaluation of Patient Preoperative Prep","status":"COMPLETED","sponsor":"Zurex Pharma, Inc.","startDate":"2016-08-03","conditions":["Surgical Skin Preparation"],"enrollment":640,"completionDate":"2017-08-03"},{"nctId":"NCT04616430","phase":"PHASE2","title":"Topical Endoxifen in Women","status":"COMPLETED","sponsor":"Atossa Therapeutics, Inc.","startDate":"2018-04-09","conditions":["Mammographic Breast Density"],"enrollment":90,"completionDate":"2019-09-04"},{"nctId":"NCT03224299","phase":"PHASE2","title":"Effectiveness of an Antimicrobial Agent for Preoperative Skin Preparation","status":"COMPLETED","sponsor":"Becton, Dickinson and Company","startDate":"2017-06-21","conditions":["Preoperative Skin Preparation"],"enrollment":131,"completionDate":"2017-10-03"},{"nctId":"NCT02618343","phase":"NA","title":"EMS Use of Isopropyl Alcohol Aromatherapy Versus Ondansetron","status":"COMPLETED","sponsor":"The University of Texas Health Science Center at San Antonio","startDate":"2016-10-04","conditions":["Nausea"],"enrollment":51,"completionDate":"2019-03-01"},{"nctId":"NCT03669224","phase":"PHASE1","title":"Effect of Nano Care Gold on Marginal Integrity of Resin Composite","status":"COMPLETED","sponsor":"Cairo University","startDate":"2019-11-01","conditions":["Caries Class Ii"],"enrollment":57,"completionDate":"2021-03-19"},{"nctId":"NCT02203591","phase":"PHASE3","title":"In Vivo Efficacy Study of Patient Preoperative Preps","status":"COMPLETED","sponsor":"3M","startDate":"2014-07","conditions":["Bacterial Reduction Post-product Application"],"enrollment":738,"completionDate":"2015-03"},{"nctId":"NCT04572685","phase":"PHASE1","title":"Evaluate the PK of LY03010 Process 1 and Process 2 Drug Product vs INVEGA SUSTENNA After Intramuscular Injection in Schizophrenia Patients","status":"COMPLETED","sponsor":"Luye Pharma Group Ltd.","startDate":"2020-01-22","conditions":["Schizophrenia Patients"],"enrollment":36,"completionDate":"2020-08-20"},{"nctId":"NCT04609384","phase":"","title":"Nudging Effect of Timer on Surgical Rub","status":"UNKNOWN","sponsor":"Sygehus Lillebaelt","startDate":"2020-01-01","conditions":["Operation Wound; Infection","Bacterial Infections","Surgical Procedure, Unspecified"],"enrollment":400,"completionDate":"2023-01-01"},{"nctId":"NCT03691831","phase":"PHASE3","title":"A Study of A-101 Topical Solution for the Treatment of Common Warts","status":"COMPLETED","sponsor":"Aclaris Therapeutics, Inc.","startDate":"2018-09-13","conditions":["Common Wart"],"enrollment":502,"completionDate":"2019-07-09"},{"nctId":"NCT04600310","phase":"NA","title":"ULTRAPREP Used to Perform Skin Antisepsis Outside the Operating Room","status":"COMPLETED","sponsor":"Prep Tech, LLC","startDate":"2018-04-17","conditions":["Time Saved Performing Skin Antisepsis Process Outside the OR","Antisepsis of Skin Preparation Outside the OR"],"enrollment":114,"completionDate":"2019-01-17"},{"nctId":"NCT01857349","phase":"NA","title":"Efficacy of Surgical Preparation Solutions in Knee Surgery","status":"COMPLETED","sponsor":"Texas Tech University Health Sciences Center","startDate":"2013-04","conditions":["Arthroplasty, Replacement"],"enrollment":77,"completionDate":"2020-07-20"},{"nctId":"NCT03687372","phase":"PHASE3","title":"Study of A-101 Topical Solution for the Treatment of Common Warts","status":"COMPLETED","sponsor":"Aclaris Therapeutics, Inc.","startDate":"2018-09-17","conditions":["Common Wart"],"enrollment":503,"completionDate":"2019-09-06"},{"nctId":"NCT02760069","phase":"PHASE4","title":"Isopropyl Alcohol vs Ondansetron for Nausea in the Emergency Department","status":"COMPLETED","sponsor":"Brooke Army Medical Center","startDate":"2016-01","conditions":["Nausea"],"enrollment":122,"completionDate":"2017-11"},{"nctId":"NCT03489512","phase":"PHASE4","title":"Comparison Trial for Chloraprep Versus Aqueous Chlorhexidine (2%) for the Prevention of Catheter-related Bacteremia","status":"WITHDRAWN","sponsor":"Instituto de Investigacion Sanitaria La Fe","startDate":"2019-10-01","conditions":["Sepsis Affecting Skin","Central Venous Catheter Related Bacteremia"],"enrollment":0,"completionDate":"2021-04-01"},{"nctId":"NCT04403191","phase":"","title":"Usage of Multiple Drugs in Treatment of Postoperative Vomiting After Laparoscopic Appendectomy","status":"COMPLETED","sponsor":"King Abdul Aziz Specialist Hospital","startDate":"2019-03-10","conditions":["to Treat the Vomiting Frequently Occur Post-laparoscopic by Different Anti Emetic Drugs"],"enrollment":240,"completionDate":"2020-02-10"},{"nctId":"NCT02351258","phase":"NA","title":"Community Central Line Infection Prevention Trial","status":"COMPLETED","sponsor":"Johns Hopkins University","startDate":"2015-11","conditions":["Infection"],"enrollment":16,"completionDate":"2019-09-09"},{"nctId":"NCT04344275","phase":"NA","title":"The Immediate Effects of Kinesio-Taping on Scapular Muscle Endurance and Strength in Asymptomatic Subjects","status":"COMPLETED","sponsor":"Gazi University","startDate":"2018-09-15","conditions":["Asymptomatic Subjects"],"enrollment":39,"completionDate":"2019-08-15"},{"nctId":"NCT02990013","phase":"EARLY_PHASE1","title":"AvenovaTM as a Sterile Skin Preparation Agent","status":"COMPLETED","sponsor":"University of Miami","startDate":"2018-12-01","conditions":["Cleaning Product Causing Toxic Effect"],"enrollment":21,"completionDate":"2019-12-20"},{"nctId":"NCT03016221","phase":"NA","title":"Local Changes of Skin Characteristics After an Application of a Topical Product With a Warming or Cooling Effect","status":"COMPLETED","sponsor":"University of Applied Sciences and Arts of Southern Switzerland","startDate":"2017-05-01","conditions":["Healthy"],"enrollment":90,"completionDate":"2019-12-06"},{"nctId":"NCT03596216","phase":"NA","title":"Neuromodulation in Professional Dancers","status":"COMPLETED","sponsor":"University of Seville","startDate":"2018-07-24","conditions":["Rehabilitation","Sports Physical Therapy","Sport Performance","Dance"],"enrollment":51,"completionDate":"2018-08-17"},{"nctId":"NCT03757143","phase":"PHASE4","title":"Chlorhexidine-Alcohol Versus Povidone Iodine-Alcohol, Combined or Not With Use of a Bundle of New Devices, for Prevention of Intravascular-catheter Colonization and Catheter Failure","status":"COMPLETED","sponsor":"Poitiers University Hospital","startDate":"2019-01-07","conditions":["Intravascular-catheter Colonization","Catheter Failure"],"enrollment":1000,"completionDate":"2019-09-27"},{"nctId":"NCT03466489","phase":"NA","title":"Floraseal Versus Iodine Impregnated Adhesive Drapes","status":"WITHDRAWN","sponsor":"University of Miami","startDate":"2018-01-01","conditions":["Surgical Site Infection","Surgical Wound Infection"],"enrollment":0,"completionDate":"2020-02-01"},{"nctId":"NCT03393819","phase":"NA","title":"Efficacy of Surgical Skin Preparation Solutions in Hip Arthroplasty Surgery","status":"COMPLETED","sponsor":"Lakehead University","startDate":"2014-10-29","conditions":["Arthroplasty, Hip Replacement","Infection, Postoperative Wound"],"enrollment":105,"completionDate":"2016-04-06"},{"nctId":"NCT02225912","phase":"PHASE4","title":"A Study to Evaluate the Efficacy of the Nasal Antiseptic, PrevinC, When Administered for the RiskReduction of Rhinitis in Subjects Who Work for Child Day Care Centers","status":"COMPLETED","sponsor":"BioHealth Technologies Inc.","startDate":"2005-02","conditions":["Upper Respiratory Infections"],"enrollment":0,"completionDate":"2005-05"},{"nctId":"NCT03229824","phase":"NA","title":"Use of Clorhexidine Dressings to Reduce Surgical Site Infections in Breast Cancer Surgery. A Controlled Clinical Trial","status":"COMPLETED","sponsor":"National Institute of Cancerología","startDate":"2016-10-03","conditions":["Breast Cancer"],"enrollment":116,"completionDate":"2018-05-30"},{"nctId":"NCT03656588","phase":"NA","title":"Does the Addition of Hydrogen Peroxide to Chlorhexidine Skin Prep to Treat P. Acnes in the Shoulder","status":"UNKNOWN","sponsor":"Rothman Institute Orthopaedics","startDate":"2018-04-16","conditions":["Propionibacterium Infection"],"enrollment":100,"completionDate":"2019-02"},{"nctId":"NCT01233050","phase":"NA","title":"Efficacy Comparison of Two Preoperative Skin Antisepsis Preparations in Colorectal Surgery","status":"COMPLETED","sponsor":"University of Pennsylvania","startDate":"2010-12","conditions":["Colorectal Surgery"],"enrollment":802,"completionDate":"2015-02"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{"route":"Topical","formulation":"Aerosol, Cloth","formulations":[{"form":"AEROSOL","route":"TOPICAL","productName":"ADCLEAN - Medical"},{"form":"AEROSOL","route":"TOPICAL","productName":"Hand Sanitizer"},{"form":"AEROSOL, FOAM","route":"TOPICAL","productName":"FRESH FOAM DISINFECTANT"},{"form":"AEROSOL, FOAM","route":"TOPICAL","productName":"Hand Sanitizer Foam"},{"form":"AEROSOL, SPRAY","route":"TOPICAL","productName":"Hand Sanitizer"},{"form":"AEROSOL, SPRAY","route":"TOPICAL","productName":"I D SEPT ANTI BACTERIAL ALCOHOL BASED HAND AND SKIN DISINFECTANT"},{"form":"AEROSOL, SPRAY","route":"TOPICAL","productName":"LARA MED Antibacterial Hand Skin Cleaner"},{"form":"AEROSOL, SPRAY","route":"TOPICAL","productName":"Nitrotan"},{"form":"CLOTH","route":"CUTANEOUS","productName":"Juniper Clean 72% Alcohol Wipes"},{"form":"CLOTH","route":"EXTRACORPOREAL","productName":"Alcohol Wipes"},{"form":"CLOTH","route":"EXTRACORPOREAL","productName":"GERMICIDAL DISPOSABLE WIPE"},{"form":"CLOTH","route":"EXTRACORPOREAL","productName":"ISOPROPYL Alcohol Wipes"},{"form":"CLOTH","route":"EXTRACORPOREAL","productName":"Tri-Titans Funk Fighter Hand Sanitizing Wipes"},{"form":"CLOTH","route":"TOPICAL","productName":"disinfecting wipes"},{"form":"CLOTH","route":"TOPICAL","productName":"Alcohol Prep Pad"}]},"_patentsChecked":true,"crossReferences":{"NUI":"N0000146763","MMSL":"11314","NDDF":"002465","UNII":"ND2M416302","VUID":"4018437","CHEBI":"CHEBI:17824","VANDF":"4017589","RXNORM":"797541","UMLSCUI":"C0022237","chemblId":"CHEMBL1956007","ChEMBL_ID":"CHEMBL582","KEGG_DRUG":"D00137","DRUGBANK_ID":"DB02325","PDB_CHEM_ID":" IPA","PUBCHEM_CID":"3776","SNOMEDCT_US":"259268001","MESH_DESCRIPTOR_UI":"D019840"},"formularyStatus":[],"_enricherVersion":"v2","_offLabelChecked":true,"developmentCodes":[],"ownershipHistory":[],"publicationCount":6092,"therapeuticAreas":["Metabolic"],"atcClassification":{"source":"DrugCentral","atcCode":"D08AX05","allCodes":["D08AX05"]},"biosimilarFilings":[],"recentPublications":[],"combinationProducts":[{"brandName":"3M DuraPrep Surgical","ingredients":"isopropanol"},{"brandName":"3M SoluPrep S","ingredients":"chlorhexidine + isopropanol"},{"brandName":"ChloraPrep One-Step","ingredients":"chlorhexidine + isopropanol"},{"brandName":"Hibistat","ingredients":"chlorhexidine + isopropanol"},{"brandName":"Prevantics Maxi Swabstick","ingredients":"chlorhexidine + isopropanol"},{"brandName":"Prevantics Swab","ingredients":"chlorhexidine + isopropanol"},{"brandName":"Prevantics Swabstick","ingredients":"chlorhexidine + isopropanol"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"","enrichmentLevel":3,"visitCount":0,"regulatoryByCountry":[{"country_code":"US","regulator":"FDA","status":"approved","approval_date":null,"mah":"","brand_name_local":null,"application_number":""},{"country_code":"CA","regulator":"Health Canada","status":"approved","approval_date":null,"mah":"","brand_name_local":"","application_number":""},{"country_code":"IL","regulator":"MOH","status":"likely_approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null},{"country_code":"SG","regulator":"HSA","status":"likely_approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null},{"country_code":"AE","regulator":"MOH","status":"likely_approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null},{"country_code":"KR","regulator":"MFDS","status":"likely_approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null},{"country_code":"AU","regulator":"TGA","status":"likely_approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null},{"country_code":"GB","regulator":"MHRA","status":"likely_approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null}],"patentsNormalised":[{"patent_number":"7241065","territory":"US","patent_type":null,"expiry_date":"2023-03-14T00:00:00.000Z","status":"active","paragraph_iv_filed":false},{"patent_number":"6729786","territory":"US","patent_type":null,"expiry_date":"2023-03-14T00:00:00.000Z","status":"active","paragraph_iv_filed":false},{"patent_number":"7182536","territory":"US","patent_type":null,"expiry_date":"2023-12-30T00:00:00.000Z","status":"active","paragraph_iv_filed":false},{"patent_number":"6991394","territory":"US","patent_type":null,"expiry_date":"2024-01-31T00:00:00.000Z","status":"active","paragraph_iv_filed":false},{"patent_number":"9011897","territory":"US","patent_type":null,"expiry_date":"2025-02-08T00:00:00.000Z","status":"active","paragraph_iv_filed":false},{"patent_number":"8226971","territory":"US","patent_type":null,"expiry_date":"2025-05-06T00:00:00.000Z","status":"active","paragraph_iv_filed":false},{"patent_number":"7422388","territory":"US","patent_type":null,"expiry_date":"2027-04-25T00:00:00.000Z","status":"active","paragraph_iv_filed":false},{"patent_number":"8703828","territory":"US","patent_type":null,"expiry_date":"2028-05-23T00:00:00.000Z","status":"active","paragraph_iv_filed":false},{"patent_number":"9629368","territory":"US","patent_type":null,"expiry_date":"2028-05-23T00:00:00.000Z","status":"active","paragraph_iv_filed":false},{"patent_number":"8389583","territory":"US","patent_type":null,"expiry_date":"2029-08-09T00:00:00.000Z","status":"active","paragraph_iv_filed":false},{"patent_number":"10688291","territory":"US","patent_type":null,"expiry_date":"2034-12-20T00:00:00.000Z","status":"active","paragraph_iv_filed":false},{"patent_number":"9844654","territory":"US","patent_type":null,"expiry_date":"2036-04-24T00:00:00.000Z","status":"active","paragraph_iv_filed":false}],"trialStats":{"total":1,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T01:03:50.384158+00:00","fieldsConflicting":2,"overallConfidence":0.8},"verificationStatus":"partial","dataCompleteness":{"mechanism":false,"indications":true,"safety":false,"trials":true,"score":2}}