{"id":"isoaminile","rwe":[{"pmid":"6749701","year":"1982","title":"A comparative randomized double-blind clinical trial of isoaminile citrate and chlophedianol hydrochloride as antitussive agents.","finding":"","journal":"International journal of clinical pharmacology, therapy, and toxicology","studyType":"Clinical Study"},{"pmid":"518294","year":"1979","title":"Some cases of acute intoxications from compulsive use of isoaminile.","finding":"","journal":"Archives of toxicology","studyType":"Clinical Study"},{"pmid":"4733605","year":"1973","title":"[Drug abuse of isoaminile].","finding":"","journal":"Zeitschrift fur Rechtsmedizin. Journal of legal medicine","studyType":"Clinical Study"},{"pmid":"5431771","year":"1970","title":"Isoaminile as inhibitor of muscarinic and nicotinic ganglionic receptors.","finding":"","journal":"Pharmacology","studyType":"Clinical Study"},{"pmid":"5905421","year":"1966","title":"Isoaminile citrate as a cough suppressant.","finding":"","journal":"The Practitioner","studyType":"Clinical Study"}],"tags":[{"label":"isoaminile","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"R05DB04","category":"atc"},{"label":"Active","category":"status"},{"label":"Antitussive Agents","category":"pharmacology"},{"label":"Central Nervous System Agents","category":"pharmacology"},{"label":"Respiratory System Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"aprecon","offLabel":[],"synonyms":["isoaminile","dimyril","isoaminil","aprecon","isoaminile citrate","peracon"],"timeline":[],"approvals":[],"brandName":"Aprecon","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"isoaminile","explanation":"Imagine your body's cells have locks on them, and Aprecon has a key that fits into those locks. When Aprecon binds to its target, it helps to regulate the activity of the cells, leading to a therapeutic effect. This process is crucial for treating various diseases, but the exact mechanism of Aprecon is not well understood.","oneSentence":"Aprecon works by interacting with a specific molecular target to produce a therapeutic effect.","technicalDetail":"Aprecon's mechanism of action involves binding to a specific receptor or enzyme, modulating its activity, and ultimately influencing downstream signaling pathways to produce its therapeutic effect."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1487","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ISOAMINILE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T14:00:31.794597","biosimilars":[],"competitors":[{"drugName":"benzonatate","drugSlug":"benzonatate","fdaApproval":"1958-02-10","genericCount":13,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"pentoxyverine","drugSlug":"pentoxyverine","fdaApproval":"","relationship":"same-class"},{"drugName":"clofedanol","drugSlug":"clofedanol","fdaApproval":"","relationship":"same-class"}],"genericName":"isoaminile","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"benzonatate","brandName":"benzonatate","genericName":"benzonatate","approvalYear":"1958","relationship":"same-class"},{"drugId":"pentoxyverine","brandName":"pentoxyverine","genericName":"pentoxyverine","approvalYear":"","relationship":"same-class"},{"drugId":"clofedanol","brandName":"clofedanol","genericName":"clofedanol","approvalYear":"","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"003984","UNII":"R4823W2PQL","CHEBI":"CHEBI:134996","INN_ID":"1076","RXNORM":"27866","UMLSCUI":"C0063912","ChEMBL_ID":"CHEMBL2105002","KEGG_DRUG":"D01490","DRUGBANK_ID":"DB08944","PUBCHEM_CID":"6481","SNOMEDCT_US":"349989006","SECONDARY_CAS_RN":"28416-66-2","MESH_SUPPLEMENTAL_RECORD_UI":"C011001"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":6,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"R05DB04","allCodes":["R05DB04"]},"biosimilarFilings":[],"recentPublications":[{"date":"1982 Aug","pmid":"6749701","title":"A comparative randomized double-blind clinical trial of isoaminile citrate and chlophedianol hydrochloride as antitussive agents.","journal":"International journal of clinical pharmacology, therapy, and toxicology"},{"date":"1979 Sep","pmid":"518294","title":"Some cases of acute intoxications from compulsive use of isoaminile.","journal":"Archives of toxicology"},{"date":"1973 Apr 30","pmid":"4733605","title":"[Drug abuse of isoaminile].","journal":"Zeitschrift fur Rechtsmedizin. Journal of legal medicine"},{"date":"1970","pmid":"5431771","title":"Isoaminile as inhibitor of muscarinic and nicotinic ganglionic receptors.","journal":"Pharmacology"},{"date":"1966 Mar","pmid":"5905421","title":"Isoaminile citrate as a cough suppressant.","journal":"The Practitioner"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Aprecon, also known as Isoaminile, is a small molecule drug of the isoaminile class. Its original development is attributed to an unknown entity, and its current ownership is also unclear. The target and indications for Aprecon are not specified, and its commercial status, including FDA approval and patent status, is unknown. Aprecon's pharmacokinetic properties, such as half-life and bioavailability, are also not documented. Further research is necessary to understand the drug's clinical profile and safety considerations.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}