{"id":"iron-oligosaccharide","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal disturbance (nausea, constipation, abdominal discomfort)"},{"rate":null,"effect":"Dark stools"},{"rate":null,"effect":"Headache"}]},"_chembl":{"chemblId":"CHEMBL364285","moleculeType":"Small molecule","molecularWeight":"976.87"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Iron oligosaccharide is an oral iron formulation where iron is complexed with oligosaccharides, which stabilize the iron and facilitate its absorption in the GI tract. This approach aims to improve bioavailability and reduce gastrointestinal side effects compared to traditional iron salts. The iron is then utilized by the body for hemoglobin synthesis and other iron-dependent processes.","oneSentence":"Iron oligosaccharide delivers iron in a carbohydrate-stabilized form that is absorbed through the gastrointestinal tract to replenish iron stores and treat iron deficiency.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:17:11.580Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Iron deficiency anemia"},{"name":"Iron supplementation in patients with chronic kidney disease"}]},"trialDetails":[{"nctId":"NCT06038656","phase":"NA","title":"Exercise and Galactooligosaccharide Supplementation on Inflammation and Iron Absorption (FexerGOS)","status":"COMPLETED","sponsor":"North-West University, South Africa","startDate":"2024-03-01","conditions":"Resistance Exercise","enrollment":22},{"nctId":"NCT04931641","phase":"NA","title":"Potential of Prebiotic Galacto-oligosaccharides in Improving Efficacy and Safety of Oral Iron Supplementation in HIV-infected Children","status":"COMPLETED","sponsor":"Swiss Federal Institute of Technology","startDate":"2021-08-01","conditions":"Iron Deficiency, HIV","enrollment":86},{"nctId":"NCT03866837","phase":"NA","title":"Prebiotic GOS and Lactoferrin With Iron Supplements","status":"COMPLETED","sponsor":"Columbia University","startDate":"2020-01-15","conditions":"Iron-deficiency","enrollment":288},{"nctId":"NCT04855266","phase":"PHASE2","title":"Iron Sucrose in Patients With Iron Deficiency and POTS","status":"WITHDRAWN","sponsor":"Mayo Clinic","startDate":"2021-04","conditions":"Iron-deficiency, Postural Orthostatic Tachycardia Syndrome","enrollment":""},{"nctId":"NCT04774016","phase":"NA","title":"Iron Absorption From an Iron-fortified Follow-up Formula With Added Synbiotic or Human Milk Oligosaccharides","status":"COMPLETED","sponsor":"Société des Produits Nestlé (SPN)","startDate":"2020-11-18","conditions":"Iron Absorption","enrollment":82},{"nctId":"NCT04163406","phase":"NA","title":"The Effect of Human Milk Oligosaccharides and Galacto-oligosaccharides on Iron Absorption in Kenyan Infants","status":"COMPLETED","sponsor":"Swiss Federal Institute of Technology","startDate":"2019-11-21","conditions":"Anemia, Iron-deficiency","enrollment":55},{"nctId":"NCT04194255","phase":"NA","title":"The Effect of Different Prebiotics on Iron Absorption From High Dose Iron Supplements","status":"COMPLETED","sponsor":"Swiss Federal Institute of Technology","startDate":"2020-07-20","conditions":"Iron-deficiency","enrollment":30},{"nctId":"NCT03996421","phase":"NA","title":"Determination of Iron Absorption Mechanism From Ferrous Fumarate With GOS","status":"COMPLETED","sponsor":"Isabelle Herter-Aeberli","startDate":"2019-10-23","conditions":"Low Iron Stores","enrollment":12},{"nctId":"NCT03762148","phase":"NA","title":"Determination of a Dose-dependent Effect of GOS on Iron Absorption, and Addition of Vitamin C","status":"COMPLETED","sponsor":"Isabelle Herter-Aeberli","startDate":"2019-04-01","conditions":"Iron-deficiency","enrollment":46},{"nctId":"NCT03325270","phase":"NA","title":"Effect of Prebiotics on Iron Absorption in Women With Low Iron Stores","status":"COMPLETED","sponsor":"Swiss Federal Institute of Technology","startDate":"2018-01-10","conditions":"Iron-deficiency","enrollment":46},{"nctId":"NCT02666417","phase":"NA","title":"Iron Absorption From a Micronutrient Powder Containing Galacto-oligosaccharides (GOS)","status":"COMPLETED","sponsor":"Swiss Federal Institute of Technology","startDate":"2016-01","conditions":"Anemia, Iron-Deficiency","enrollment":64},{"nctId":"NCT02989311","phase":"NA","title":"Effect of Timing of Micronutrient Powder Consumption on Iron Absorption in Infants","status":"COMPLETED","sponsor":"Swiss Federal Institute of Technology","startDate":"2016-08","conditions":"Anemia, Iron Deficiency","enrollment":23},{"nctId":"NCT02728141","phase":"NA","title":"Healthy Infant Development Project - Sucrose Component","status":"COMPLETED","sponsor":"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","startDate":"2009-11","conditions":"Iron Deficiency","enrollment":424},{"nctId":"NCT01840384","phase":"NA","title":"Efficacy Study of Multiple Micro Nutrients Supplementation","status":"UNKNOWN","sponsor":"PT. Sari Husada","startDate":"2013-07","conditions":"Anemia, Iron-deficiency","enrollment":239},{"nctId":"NCT01017614","phase":"PHASE3","title":"Iron Oligosaccharide in Inflammatory Bowel Disease Subjects With Iron Deficiency Anaemia","status":"COMPLETED","sponsor":"Pharmacosmos A/S","startDate":"2009-10","conditions":"Inflammatory Bowel Disease","enrollment":350},{"nctId":"NCT00223964","phase":"PHASE4","title":"Study of the Efficacy of Two Doses of Ferrlecit in the Treatment of Iron Deficiency in Pediatric Hemodialysis Patients","status":"COMPLETED","sponsor":"Watson Pharmaceuticals","startDate":"2003-06","conditions":"Anemia","enrollment":59},{"nctId":"NCT00224055","phase":"PHASE4","title":"Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients","status":"COMPLETED","sponsor":"Watson Pharmaceuticals","startDate":"2003-04","conditions":"Anemia, Iron-Deficiency, Kidney Failure, Chronic","enrollment":89},{"nctId":"NCT00224042","phase":"PHASE4","title":"Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients Receiving Erythropoietic Agents","status":"COMPLETED","sponsor":"Watson Pharmaceuticals","startDate":"2003-04","conditions":"Anemia, Iron-Deficiency, Kidney Failure, Chronic","enrollment":52},{"nctId":"NCT00534144","phase":"PHASE1","title":"Comparison Between Effects of Two Iron Preparations on Protein in the Urine","status":"COMPLETED","sponsor":"Watson Pharmaceuticals","startDate":"2007-09","conditions":"Kidney Failure, Chronic, Anemia, Iron-Deficiency","enrollment":74},{"nctId":"NCT00661999","phase":"PHASE3","title":"Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer","status":"COMPLETED","sponsor":"Mayo Clinic","startDate":"2006-01","conditions":"Anemia, Leukemia, Lymphoma","enrollment":502},{"nctId":"NCT00224003","phase":"PHASE4","title":"Study of the Safety and Efficacy of Ferrlecit® Maintenance Dosing in Pediatric Hemodialysis Patients","status":"COMPLETED","sponsor":"Watson Pharmaceuticals","startDate":"2003-04","conditions":"Anemia","enrollment":23},{"nctId":"NCT00537186","phase":"PHASE3","title":"A Study of Iron Oligosaccharide in CHF Patients","status":"COMPLETED","sponsor":"Pharmacosmos A/S","startDate":"2007-06","conditions":"Heart Failure, Congestive","enrollment":20},{"nctId":"NCT00536666","phase":"PHASE3","title":"A Study of Iron Oligosaccharide in Chronic Kidney Disease Patients","status":"COMPLETED","sponsor":"Pharmacosmos A/S","startDate":"2007-05","conditions":"Chronic Kidney Disease, Anemia, Iron-Deficiency","enrollment":182},{"nctId":"NCT00255385","phase":"PHASE3","title":"Efficacy of Bifidus DR10 and Oligo Saccharides / Micronutrient Fortification of Milk","status":"COMPLETED","sponsor":"Johns Hopkins Bloomberg School of Public Health","startDate":"2002-04","conditions":"Diarrhea, Pneumonia, Febrile Illness","enrollment":1200}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["MonoFer"],"phase":"phase_3","status":"active","brandName":"Iron oligosaccharide","genericName":"Iron oligosaccharide","companyName":"Pharmacosmos A/S","companyId":"pharmacosmos-a-s","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Iron oligosaccharide delivers iron in a carbohydrate-stabilized form that is absorbed through the gastrointestinal tract to replenish iron stores and treat iron deficiency. Used for Iron deficiency anemia, Iron supplementation in patients with chronic kidney disease.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}