{"id":"iron-dextran-complex-injection-infed","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site reactions (pain, discoloration)"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Arthralgia"},{"rate":"rare","effect":"Anaphylactic reactions"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The dextran coating protects iron from premature precipitation and allows it to be transported to bone marrow macrophages and hepatocytes. Once internalized, the iron is released and utilized for erythropoiesis and other physiological iron-dependent processes. This parenteral formulation bypasses gastrointestinal absorption limitations and is used to rapidly replenish iron stores in iron-deficiency anemia.","oneSentence":"Iron-dextran complex provides bioavailable iron that is taken up by the reticuloendothelial system and released for incorporation into hemoglobin and other iron-dependent proteins.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:50:16.914Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Iron-deficiency anemia in patients unable to tolerate or absorb oral iron"}]},"trialDetails":[],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":3,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["INFeD"],"phase":"marketed","status":"active","brandName":"Iron-Dextran Complex Injection [InFed]","genericName":"Iron-Dextran Complex Injection [InFed]","companyName":"Oregon Health and Science University","companyId":"oregon-health-and-science-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Iron-dextran complex provides bioavailable iron that is taken up by the reticuloendothelial system and released for incorporation into hemoglobin and other iron-dependent proteins. Used for Iron-deficiency anemia in patients unable to tolerate or absorb oral iron.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":false,"score":3}}