{"id":"iprazochrome","rwe":[{"pmid":"40356616","year":"2025","title":"Consulting, diagnosis and treatment patterns in migraine: results from the Migraine in Poland cross-sectional survey.","finding":"","journal":"Therapeutic advances in neurological disorders","studyType":"Clinical Study"},{"pmid":"10463251","year":"1999","title":"[Controlled study of iprazochrome effectiveness (Divascan) in prophylactic treatment of migraine].","finding":"","journal":"Neurologia i neurochirurgia polska","studyType":"Clinical Study"},{"pmid":"9380219","year":"1997","title":"[Iprazochrome in migraine prevention. No concerns regarding longer-term administration].","finding":"","journal":"Der Nervenarzt","studyType":"Clinical Study"},{"pmid":"9380218","year":"1997","title":"[Side-effect free interval treatment of migraine. The serotonin antagonist iprazochrome].","finding":"","journal":"Der Nervenarzt","studyType":"Clinical Study"},{"pmid":"8740149","year":"1996","title":"Effects of antimigraine drugs on retinal spreading depression.","finding":"","journal":"Naunyn-Schmiedeberg's archives of pharmacology","studyType":"Clinical Study"}],"tags":[{"label":"iprazochrome","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"N02CX03","category":"atc"},{"label":"Active","category":"status"},{"label":"Neurotransmitter Agents","category":"pharmacology"},{"label":"Serotonin Agents","category":"pharmacology"},{"label":"Serotonin Antagonists","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"divascan","offLabel":[],"synonyms":["iprazochrome","divascan","isopropylnoradenochrome monosemicarbazone","isopropylnoradrenochrome monosemicarbazone"],"timeline":[],"approvals":[],"brandName":"Divascan","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"iprazochrome","explanation":"Imagine your body's cells are like locks, and Divascan is a key that fits into those locks. When it binds to the right lock, it helps to turn the lock and unlock the cell's normal functioning, which can help to treat certain medical conditions. This process is called a pharmacological interaction, and it's how many medications work to produce their effects.","oneSentence":"Divascan works by binding to specific proteins in the body to produce its therapeutic effects.","technicalDetail":"Divascan is a small molecule that interacts with its target through a reversible binding mechanism, potentially modulating protein function and influencing downstream signaling pathways."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Iprazochrome","title":"Iprazochrome","extract":"Iprazochrome is an antimigraine agent used for prophylaxis of the attacks. It is also indicated for diabetic retinopathy."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1476","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=IPRAZOCHROME","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Iprazochrome","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T13:59:51.733734","biosimilars":[],"competitors":[{"drugName":"clonidine","drugSlug":"clonidine","fdaApproval":"1974-09-03","patentExpiry":"Sep 8, 2031","patentStatus":"Patent protected","relationship":"same-class"}],"genericName":"iprazochrome","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"clonidine","brandName":"clonidine","genericName":"clonidine","approvalYear":"1974","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"006714","UNII":"903A9K181P","CHEBI":"CHEBI:135088","INN_ID":"4427","RXNORM":"51486","UMLSCUI":"C0123902","ChEMBL_ID":"CHEMBL4297107","KEGG_DRUG":"D07297","DRUGBANK_ID":"DB13541","PUBCHEM_CID":"65594","MESH_SUPPLEMENTAL_RECORD_UI":"C009742"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":8,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"N02CX03","allCodes":["N02CX03"]},"biosimilarFilings":[],"recentPublications":[{"date":"2025","pmid":"40356616","title":"Consulting, diagnosis and treatment patterns in migraine: results from the Migraine in Poland cross-sectional survey.","journal":"Therapeutic advances in neurological disorders"},{"date":"1999 Mar-Apr","pmid":"10463251","title":"[Controlled study of iprazochrome effectiveness (Divascan) in prophylactic treatment of migraine].","journal":"Neurologia i neurochirurgia polska"},{"date":"1997 Aug","pmid":"9380219","title":"[Iprazochrome in migraine prevention. No concerns regarding longer-term administration].","journal":"Der Nervenarzt"},{"date":"1997 Aug","pmid":"9380218","title":"[Side-effect free interval treatment of migraine. The serotonin antagonist iprazochrome].","journal":"Der Nervenarzt"},{"date":"1996 Apr","pmid":"8740149","title":"Effects of antimigraine drugs on retinal spreading depression.","journal":"Naunyn-Schmiedeberg's archives of pharmacology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Divascan (IPRAZOCHROME) is a small molecule drug in the iprazochrome class, but details about its target, FDA approval status, and approved indications are unknown. As a small molecule, it is designed to interact with specific biological targets to produce its therapeutic effects. The commercial status of Divascan is also unclear, with no information available on whether it is patented or available as a generic. Further research is needed to understand the safety considerations and potential side effects of this medication. Overall, more information is required to fully assess the characteristics and potential uses of Divascan.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}