{"id":"ionic-iron","safety":{"commonSideEffects":[{"rate":"10-30","effect":"Gastrointestinal upset (nausea, constipation, abdominal discomfort)"},{"rate":null,"effect":"Dark stools"},{"rate":"5-15","effect":"Abdominal pain"},{"rate":"5-10","effect":"Diarrhea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Ionic iron (ferrous or ferric salts) is absorbed in the gastrointestinal tract and incorporated into hemoglobin and myoglobin, as well as iron-dependent enzymes. It corrects iron deficiency anemia by replenishing total body iron stores and enabling normal erythropoiesis. This is a replacement therapy for iron deficiency states.","oneSentence":"Ionic iron replaces depleted iron stores to restore hemoglobin synthesis and oxygen-carrying capacity in the blood.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:50:07.756Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Iron deficiency anemia"},{"name":"Iron supplementation in pregnancy"},{"name":"Iron deficiency due to chronic blood loss"}]},"trialDetails":[{"nctId":"NCT07391371","phase":"PHASE4","title":"Alternate-day Versus Daily Oral Iron Therapy in Children With Iron Deficiency Anaemia","status":"NOT_YET_RECRUITING","sponsor":"University of Medicine, Mandalay","startDate":"2026-02-01","conditions":"Iron Deficiency Anemia","enrollment":60},{"nctId":"NCT01865175","phase":"PHASE4","title":"A Pilot Study Comparing Tolerance of Oral Heme Iron Polypeptide With Oral Ionic Iron","status":"WITHDRAWN","sponsor":"Milton S. Hershey Medical Center","startDate":"2016-01","conditions":"Iron Deficiency","enrollment":""}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Ferrous Sulphate"],"phase":"marketed","status":"active","brandName":"ionic iron","genericName":"ionic iron","companyName":"Milton S. Hershey Medical Center","companyId":"milton-s-hershey-medical-center","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ionic iron replaces depleted iron stores to restore hemoglobin synthesis and oxygen-carrying capacity in the blood. Used for Iron deficiency anemia, Iron supplementation in pregnancy, Iron deficiency due to chronic blood loss.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}