{"id":"ioglicic-acid","rwe":[{"pmid":"3629121","year":"1987","title":"Morphological and functional abnormalities in platelets exposed in vitro to ioglicinic acid, a new ionic contrast medium.","finding":"","journal":"La Ricerca in clinica e in laboratorio","studyType":"Clinical Study"},{"pmid":"631971","year":"1978","title":"Pharmacokinetics and clinical studies of ioglicinate, a new contrast medium for intravenous urography.","finding":"","journal":"International journal of clinical pharmacology and biopharmacy","studyType":"Clinical Study"}],"tags":[{"label":"ioglicic acid","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"V08AA06","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"ioglicinate","offLabel":[],"synonyms":["ioglicic acid","ioglicinate"],"timeline":[],"approvals":[],"brandName":"Ioglicinate","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"ioglicic acid","explanation":"Think of it like a key fitting into a lock - ioglicinate is the key that blocks the action of a particular enzyme, which is involved in a specific process in the body. This can help to prevent or treat certain conditions by altering the balance of chemicals in the body. By blocking the enzyme, ioglicinate can help to reduce the symptoms of a particular disease or condition.","oneSentence":"Ioglicinate works by binding to and inhibiting the activity of a specific enzyme or protein.","technicalDetail":"Ioglicinate is a competitive inhibitor of the enzyme, binding to its active site and preventing the conversion of substrate to product. This results in a decrease in the activity of the enzyme, leading to a reduction in the downstream effects of the enzyme's action."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Ioglicic_acid","title":"Ioglicic acid","extract":"Ioglicic acid is a pharmaceutical drug that was used as an iodinated contrast medium for X-ray imaging, in form of its salt meglumine ioglicate. Uses included imaging of the brain, the aorta and femoral arteries, and the urinary system."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4580","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=IOGLICIC ACID","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Ioglicic_acid","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T13:59:17.828345","biosimilars":[],"competitors":[{"drugName":"diatrizoate","drugSlug":"diatrizoate","fdaApproval":"1954-11-26","genericCount":2,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"metrizoic acid","drugSlug":"metrizoic-acid","fdaApproval":"1973-11-17","relationship":"same-class"},{"drugName":"iodamide","drugSlug":"iodamide","fdaApproval":"1978-07-25","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"iotalamic acid","drugSlug":"iotalamic-acid","fdaApproval":"1963-09-30","relationship":"same-class"},{"drugName":"acetrizoic acid","drugSlug":"acetrizoic-acid","fdaApproval":"","relationship":"same-class"}],"genericName":"ioglicic acid","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"diatrizoate","brandName":"diatrizoate","genericName":"diatrizoate","approvalYear":"1954","relationship":"same-class"},{"drugId":"metrizoic-acid","brandName":"metrizoic acid","genericName":"metrizoic acid","approvalYear":"1973","relationship":"same-class"},{"drugId":"iodamide","brandName":"iodamide","genericName":"iodamide","approvalYear":"1978","relationship":"same-class"},{"drugId":"iotalamic-acid","brandName":"iotalamic acid","genericName":"iotalamic acid","approvalYear":"1963","relationship":"same-class"},{"drugId":"acetrizoic-acid","brandName":"acetrizoic acid","genericName":"acetrizoic acid","approvalYear":"","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"3LGR5S8101","CHEBI":"CHEBI:135999","INN_ID":"3724","UMLSCUI":"C0063806","ChEMBL_ID":"CHEMBL2105024","KEGG_DRUG":"D04574","DRUGBANK_ID":"DB13701","PUBCHEM_CID":"65437","MESH_SUPPLEMENTAL_RECORD_UI":"C016525"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":2,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"V08AA06","allCodes":["V08AA06"]},"biosimilarFilings":[],"recentPublications":[{"date":"1987 Apr-Jun","pmid":"3629121","title":"Morphological and functional abnormalities in platelets exposed in vitro to ioglicinic acid, a new ionic contrast medium.","journal":"La Ricerca in clinica e in laboratorio"},{"date":"1978 Feb","pmid":"631971","title":"Pharmacokinetics and clinical studies of ioglicinate, a new contrast medium for intravenous urography.","journal":"International journal of clinical pharmacology and biopharmacy"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ioglicinate, also known as ioglicic acid, is a small molecule drug of the ioglicic acid class. Its original development and current ownership are not specified in the provided facts. The target and approved indications of ioglicinate are unknown. Its commercial status, including patent status and generic availability, is also unclear. Further information on its pharmacokinetic properties, such as half-life and bioavailability, is not available.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}