{"id":"iofetamine-123i","rwe":[],"tags":[{"label":"Iofetamine (123I)","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"iofetamine i 123","offLabel":[],"synonyms":["Iofetamine I 123","Iofetamine (123I)","123I-IMP","123I-Spectamine"],"timeline":[],"brandName":"Iofetamine I 123","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"Iofetamine (123I)","explanation":"Imagine a special kind of dye that is attached to a tiny amount of radioactive material. When this dye is injected into the body, it travels to specific areas and binds to certain cells or tissues. This allows doctors to use a special camera to take pictures of the body and see where the dye has accumulated, which can help diagnose certain conditions.","oneSentence":"Iofetamine I 123 is a radioactive compound that binds to specific sites in the body, allowing for diagnostic imaging.","technicalDetail":"Iofetamine I 123 is a technetium-99m (99mTc) labeled radiopharmaceutical that binds to the dopamine transporter in the brain, allowing for imaging of the dopaminergic system."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Iofetamine_(123I)","title":"Iofetamine (123I)","extract":"Iofetamine, brand names Perfusamine, SPECTamine), or N-isopropyl-(123I)-p-iodoamphetamine (IMP), is a lipid-soluble amine and radiopharmaceutical drug used in cerebral blood perfusion imaging with single-photon emission computed tomography (SPECT). Labeled with the radioactive isotope iodine-123, it is approved for use in the United States as a diagnostic aid in determining the localization of and in the evaluation of non-lacunar stroke and complex partial seizures, as well as in the early diagnosis of Alzheimer's disease."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1459","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=Iofetamine (123I)","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Iofetamine_(123I)","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T08:19:08.774677","biosimilars":[],"competitors":[],"genericName":"iofetamine (123i)","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"LV23B78IJC","CHEBI":"CHEBI:31708","INN_ID":"5526","UMLSCUI":"C0917914","ChEMBL_ID":"CHEMBL1200360","DRUGBANK_ID":"DB09480","PUBCHEM_CID":"156375","SECONDARY_CAS_RN":"75917-92-9"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":546,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Iofetamine I 123 (Iofetamine (123I)) is a small molecule radiopharmaceutical drug of the iofetamine class. Its exact target and mechanism of action are unknown, but it is used for diagnostic purposes. The commercial status of Iofetamine I 123 is unclear, and it may be patented or have generic manufacturers. Iofetamine I 123 is not FDA-approved for any indications, and its half-life, bioavailability, and safety considerations are unknown. Further research is needed to fully understand this drug.","enrichmentLevel":3,"visitCount":2,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}