{"id":"iodohippurate-sodium-i131","rwe":[{"pmid":"30000624","year":"2006","title":"Iodohippurate Sodium I 131.","finding":"","journal":"","studyType":"Clinical Study"},{"pmid":"24589448","year":"2014","title":"Microwave assistance of labeling hippuric acid by I-131.","finding":"","journal":"Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine","studyType":"Clinical Study"},{"pmid":"19808227","year":"2009","title":"Renal function in glycogen storage disease type I, natural course, and renopreservative effects of ACE inhibition.","finding":"","journal":"Clinical journal of the American Society of Nephrology : CJASN","studyType":"Clinical Study"},{"pmid":"9988071","year":"1999","title":"I-131 orthoiodohippurate assessment of renal function after heart transplantation.","finding":"","journal":"Clinical nuclear medicine","studyType":"Clinical Study"},{"pmid":"8719353","year":"1995","title":"Extended measurement of glomerular filtration rate and effective renal plasma flow in ambulatory patients.","finding":"","journal":"Scandinavian journal of urology and nephrology","studyType":"Clinical Study"}],"tags":[{"label":"iodohippurate sodium I131","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"hippuran i131","offLabel":[],"synonyms":["iodohippurate sodium I131","Hippuran-131","Hippuran I131"],"timeline":[],"approvals":[],"brandName":"Hippuran I131","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"iodohippurate sodium I131","explanation":"Imagine your kidneys as filters that clean your blood. Hippuran I131 is a special substance that gets taken up by these filters and then gets excreted in your urine. By watching how quickly this substance is removed from your body, doctors can get a picture of how well your kidneys are working.","oneSentence":"Hippuran I131 works by being taken up by the kidneys and excreted in the urine, allowing for imaging of the renal function.","technicalDetail":"Iodohippurate sodium I131 is a radiopharmaceutical that is taken up by the renal tubular cells and excreted in the urine, allowing for measurement of renal plasma flow and glomerular filtration rate."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4828","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=iodohippurate sodium I131","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:07:45.604112","biosimilars":[],"competitors":[],"genericName":"iodohippurate sodium i131","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"9BRV734R3E","CHEBI":"CHEBI:134740","VANDF":"4017584","INN_ID":"2806","RXNORM":"91540","UMLSCUI":"C0304987","ChEMBL_ID":"CHEMBL1200763","DRUGBANK_ID":"DB09382","PUBCHEM_CID":"23663553"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":100,"therapeuticAreas":["Nephrology"],"biosimilarFilings":[],"recentPublications":[{"date":"2006","pmid":"30000624","title":"Iodohippurate Sodium I 131.","journal":""},{"date":"2014 Jul","pmid":"24589448","title":"Microwave assistance of labeling hippuric acid by I-131.","journal":"Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine"},{"date":"2009 Nov","pmid":"19808227","title":"Renal function in glycogen storage disease type I, natural course, and renopreservative effects of ACE inhibition.","journal":"Clinical journal of the American Society of Nephrology : CJASN"},{"date":"1999 Feb","pmid":"9988071","title":"I-131 orthoiodohippurate assessment of renal function after heart transplantation.","journal":"Clinical nuclear medicine"},{"date":"1995 Dec","pmid":"8719353","title":"Extended measurement of glomerular filtration rate and effective renal plasma flow in ambulatory patients.","journal":"Scandinavian journal of urology and nephrology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Hippuran I131 (iodohippurate sodium I131) is a small molecule drug in the iodohippurate sodium I131 class. Its exact target and mechanism of action are unknown, but it is used to treat certain conditions. The commercial status of Hippuran I131 is unclear, and it may be patented or have generic manufacturers. Key safety considerations are not well-documented. Further research is needed to fully understand this medication.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}