{"id":"iodohippurate-sodium-i125","rwe":[],"tags":[{"label":"iodohippurate sodium I125","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"hippuran i125","offLabel":[],"synonyms":["iodohippurate sodium I125","Hippuran-125","Hippuran I125"],"timeline":[],"approvals":[],"brandName":"Hippuran I125","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"iodohippurate sodium I125","explanation":"Imagine your kidneys as filters that clean your blood. Hippuran I125 is a small molecule that gets filtered out by the kidneys and then excreted into the urine. By tracing the path of this molecule, doctors can see how well the kidneys are working.","oneSentence":"Hippuran I125 works by binding to and being excreted by the kidneys, allowing for imaging of renal function.","technicalDetail":"Iodohippurate sodium I125 is a substrate for organic anion transporters in the kidneys, which facilitates its excretion and allows for imaging of renal function."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4827","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=iodohippurate sodium I125","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:01:38.349078","biosimilars":[],"competitors":[],"genericName":"iodohippurate sodium i125","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"T5536Q4O60","CHEBI":"CHEBI:134739","UMLSCUI":"C0304998","ChEMBL_ID":"CHEMBL2104818","PUBCHEM_CID":"23677973"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":10,"therapeuticAreas":["Nephrology"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Hippuran I125 (iodohippurate sodium I125) is a small molecule radiopharmaceutical in the iodohippurate sodium I125 drug class. Its exact target and mechanism of action are unknown, but it is used for diagnostic purposes. The commercial status of Hippuran I125 is unclear, and it may be patented or off-patent. Key safety considerations include the use of radioactive iodine, which requires proper handling and disposal. Further information on its approved indications, half-life, and bioavailability is not available.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}