{"id":"iodixanol-320-mgi-ml","safety":{"commonSideEffects":[{"rate":null,"effect":"Contrast-induced nephropathy (CIN)"},{"rate":null,"effect":"Hypersensitivity reactions"},{"rate":null,"effect":"Nausea and vomiting"},{"rate":null,"effect":"Flushing and warmth sensation"},{"rate":null,"effect":"Renal impairment"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Iodixanol contains iodine atoms that attenuate X-ray radiation, creating contrast in radiographic imaging. As an iso-osmolar contrast medium (IOCM), it has an osmolality equal to blood plasma, which may reduce nephrotoxicity and adverse reactions compared to hyperosmolar agents. It is used for angiographic and urographic procedures to visualize vascular and urinary anatomy.","oneSentence":"Iodixanol is a non-ionic, iso-osmolar contrast medium that provides radiographic visualization of blood vessels and body cavities by absorbing X-rays.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:40:47.994Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Coronary and peripheral angiography"},{"name":"Urography and intravenous pyelography"},{"name":"Venography"},{"name":"Computed tomography (CT) imaging"}]},"trialDetails":[{"nctId":"NCT03671603","phase":"","title":"Post-Marketing Safety Study in ST-Segment Elevation Myocardial Infarction (STEMI) Participants Undergoing Primary Percutaneous Coronary Intervention (PCI) Procedure With VISIPAQUE® as the Contrast Medium","status":"COMPLETED","sponsor":"GE Healthcare","startDate":"2018-11-05","conditions":"Coronary Artery Disease, ST-segment Elevation Myocardial Infarction","enrollment":2755},{"nctId":"NCT03119662","phase":"PHASE4","title":"A Study to Explore the Renal Safety of Visipaque Injection 320 mgI/mL in Patients With Chronic Kidney Disease","status":"TERMINATED","sponsor":"GE Healthcare","startDate":"2018-02-08","conditions":"Chronic Kidney Diseases","enrollment":4},{"nctId":"NCT00350506","phase":"NA","title":"A Trial Evaluating the Clinical Applicability, Correlation, and Modeling of Cardiac CT Using 64 Detector Row VCT","status":"TERMINATED","sponsor":"GE Healthcare","startDate":"2005-10","conditions":"Coronary Artery Disease","enrollment":77},{"nctId":"NCT00348569","phase":"NA","title":"A Study of Computed Tomography (CT) for Evaluation of Coronary Artery Blockages in Typical or Atypical Chest Pain","status":"COMPLETED","sponsor":"GE Healthcare","startDate":"2006-05","conditions":"Coronary Artery Disease","enrollment":245},{"nctId":"NCT00793182","phase":"PHASE4","title":"Effects of Contrast Media on Subjects With Stable Reduced Renal Function Undergoing Contrast-Enhanced Computed Tomography","status":"TERMINATED","sponsor":"Guerbet","startDate":"2009-01","conditions":"Renal Impairment","enrollment":6},{"nctId":"NCT01188486","phase":"NA","title":"Pulmonary Interstitial Lymphography in Early Stage Lung Cancer","status":"TERMINATED","sponsor":"Stanford University","startDate":"2010-08","conditions":"Lung Cancer, Lung Cancer Non-Small Cell Cancer (NSCLC), Lung Cancer Small Cell Lung Cancer (SCLC)","enrollment":12},{"nctId":"NCT00209430","phase":"PHASE4","title":"Renal Effects of Two Iodinated Contrast Media in Patients at Risk Undergoing Coronary Angiography","status":"COMPLETED","sponsor":"GE Healthcare","startDate":"2005-08","conditions":"Coronary Artery Disease, Renal Impairment","enrollment":408}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":21,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Visipaque"],"phase":"marketed","status":"active","brandName":"Iodixanol 320 mgI/mL","genericName":"Iodixanol 320 mgI/mL","companyName":"Guerbet","companyId":"guerbet","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Iodixanol is a non-ionic, iso-osmolar contrast medium that provides radiographic visualization of blood vessels and body cavities by absorbing X-rays. Used for Coronary and peripheral angiography, Urography and intravenous pyelography, Venography.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}