{"id":"iodinated-glycerol","rwe":[],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Common cold","category":"indication"},{"label":"Cough","category":"indication"},{"label":"Thick Bronchial Secretions","category":"indication"}],"phase":"unknown","safety":{"contraindications":["Acute abdominal pain","Acute exacerbation of asthma","Benign intracranial hypertension","Benign prostatic hyperplasia","Bradycardia","Central nervous system depression","Chronic disease of respiratory system","Conduction disorder of the heart","Decreased respiratory function","Dependent drug abuse","Disease of liver","Disorder of gallbladder","Drug AND/OR toxin-induced diarrhea","Dysfunction of sphincter of Oddi","Epilepsy","Hypothyroidism","Inflammatory bowel disease","Injury of head","Kidney disease","Lesion of brain","Low blood pressure","Mood swings","Operation on gastrointestinal tract","Primary adrenocortical insufficiency","Procedure on urinary system"]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"organidin","offLabel":[],"synonyms":["iodinated glycerol","organidin","iodopropylidene glycerol","glycerol iodinated"],"timeline":[],"approvals":[],"brandName":"Organidin","ecosystem":[{"indication":"Common cold","otherDrugs":[{"name":"acetylsalicylic acid","slug":"acetylsalicylic-acid","company":"Endo Pharms"},{"name":"acrivastine","slug":"acrivastine","company":"Auxilium Pharms Inc"},{"name":"ammonium chloride","slug":"ammonium-chloride","company":"B Braun"},{"name":"azatadine","slug":"azatadine","company":""}],"globalPrevalence":null},{"indication":"Cough","otherDrugs":[{"name":"ammonium chloride","slug":"ammonium-chloride","company":"B Braun"},{"name":"benzocaine","slug":"benzocaine","company":""},{"name":"benzonatate","slug":"benzonatate","company":"Pfizer"},{"name":"bromazine","slug":"bromazine","company":"Forest Labs"}],"globalPrevalence":null},{"indication":"Thick Bronchial Secretions","otherDrugs":[{"name":"acetylcysteine","slug":"acetylcysteine","company":"Apothecon"},{"name":"cysteine","slug":"cysteine","company":"Hospira"},{"name":"isoprenaline","slug":"isoprenaline","company":""}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your airways are like a sticky, thick honey. Organidin helps to break down this honey-like mucus, making it easier to cough up and clear out of your body. This can help relieve congestion and make breathing easier.","oneSentence":"Organidin works by helping to thin and loosen mucus in the airways, making it easier to cough up.","technicalDetail":"The exact mechanism of action of Organidin is unknown, but it is believed to work by altering the surface tension of mucus, making it easier to expel from the airways."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1454","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=iodinated%20glycerol","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=iodinated glycerol","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:07:25.971924","biosimilars":[],"competitors":[],"genericName":"iodinated glycerol","indications":{"approved":[{"name":"Common cold","source":"DrugCentral","snomedId":82272006,"regulator":"FDA"},{"name":"Cough","source":"DrugCentral","snomedId":49727002,"regulator":"FDA"},{"name":"Thick Bronchial Secretions","source":"DrugCentral","snomedId":"","regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[{"nctId":"NCT05882188","phase":"NA","title":"The Cost-effectiveness of Hysterosalpingography Versus Hysterosalpingo-foam Sonography During Fertility Work-up","status":"RECRUITING","sponsor":"Amsterdam UMC, location VUmc","startDate":"2023-09-22","conditions":["Infertility"],"enrollment":1102,"completionDate":"2027-06-01"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NUI":"N0000179159","MMSL":"d00799","NDDF":"000848","UNII":"34ON63CCO3","VUID":"4018458","CHEBI":"CHEBI:135062","VANDF":"4018458","RXNORM":"227400","UMLSCUI":"C0063750","ChEMBL_ID":"CHEMBL2105827","PUBCHEM_CID":"21852","SNOMEDCT_US":"400799002","MESH_SUPPLEMENTAL_RECORD_UI":"C015372"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":23,"therapeuticAreas":["Respiratory"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Organidin, also known as iodinated glycerol, is a small molecule modality used to treat common cold, cough, and thick bronchial secretions. However, due to the lack of available information, its exact mechanism of action and pharmacological properties are unknown. As a result, its commercial status, including whether it is patented or generic, and its off-patent status, are also unclear. Further research is needed to fully understand Organidin's properties and uses. Despite this, it is currently used to help loosen and clear mucus from the airways.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}