{"id":"investigational-varicella-vaccine-lot-3","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site erythema or swelling"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Rash"},{"rate":null,"effect":"Myalgia or fatigue"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Varicella vaccines work by introducing attenuated or inactivated varicella-zoster virus (VZV) antigen to prime both humoral and cellular immune responses. This allows the body to develop memory immunity that prevents primary varicella infection or reduces disease severity upon exposure to wild-type VZV.","oneSentence":"This investigational varicella vaccine stimulates the immune system to recognize and prevent varicella-zoster virus infection by inducing protective antibodies and cell-mediated immunity.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:17:04.540Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of varicella (chickenpox) in pediatric and/or adult populations"}]},"trialDetails":[{"nctId":"NCT06740630","phase":"PHASE3","title":"A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age","status":"RECRUITING","sponsor":"GlaxoSmithKline","startDate":"2025-01-10","conditions":"Chickenpox","enrollment":1840}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Investigational varicella vaccine_Lot 3","genericName":"Investigational varicella vaccine_Lot 3","companyName":"GlaxoSmithKline","companyId":"gsk","modality":"Biologic","firstApprovalDate":"","aiSummary":"This investigational varicella vaccine stimulates the immune system to recognize and prevent varicella-zoster virus infection by inducing protective antibodies and cell-mediated immunity. Used for Prevention of varicella (chickenpox) in pediatric and/or adult populations.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}