{"id":"intraoperative-injection-of-carbon-nanoparticles","safety":{"commonSideEffects":[{"rate":null,"effect":"Local injection site reactions"},{"rate":null,"effect":"Allergic reactions"}]},"_chembl":{"chemblId":"CHEMBL2108490","moleculeType":"Protein"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Carbon nanoparticles serve as a tracer agent that preferentially drains to and concentrates in sentinel lymph nodes, the first nodes to which cancer may spread. By visualizing these nodes intraoperatively through their black coloration, surgeons can identify and selectively remove them for pathological examination, improving staging accuracy and reducing unnecessary lymph node dissection.","oneSentence":"Carbon nanoparticles injected intraoperatively accumulate in lymph nodes to enable sentinel lymph node identification and removal during cancer surgery.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:16:42.185Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Sentinel lymph node identification and biopsy in cancer surgery"}]},"trialDetails":[{"nctId":"NCT07391514","phase":"","title":"Deep Learning-Based Intraoperative Dual-tracer Video Analysis of Sentinel Lymph Node Mapping for Metastasis Prediction in cN0 Papillary Thyroid Carcinoma","status":"COMPLETED","sponsor":"First Affiliated Hospital of Chongqing Medical University","startDate":"2024-04-01","conditions":"Papillary Thyroid Carcinoma","enrollment":131},{"nctId":"NCT06791005","phase":"PHASE3","title":"A Clinical Study on the Benefits of Carbon Nanoparticles Injection Time in Patients With Thyroid Cancer.","status":"RECRUITING","sponsor":"Second Affiliated Hospital of Xi'an Jiaotong University","startDate":"2025-01-01","conditions":"Papillary Thyroid Cancer","enrollment":400},{"nctId":"NCT04951245","phase":"PHASE3","title":"Ultrasound-assisted CNSs Mapping Versus Dual-tracer-guided Sentinel Lymph Node Biopsy","status":"COMPLETED","sponsor":"Guangdong Provincial People's Hospital","startDate":"2019-12-01","conditions":"Breast Cancer","enrollment":330}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":32,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Intraoperative Injection of Carbon Nanoparticles","genericName":"Intraoperative Injection of Carbon Nanoparticles","companyName":"Second Affiliated Hospital of Xi'an Jiaotong University","companyId":"second-affiliated-hospital-of-xi-an-jiaotong-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Carbon nanoparticles injected intraoperatively accumulate in lymph nodes to enable sentinel lymph node identification and removal during cancer surgery. Used for Sentinel lymph node identification and biopsy in cancer surgery.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}