{"id":"insulin-detemir-mixed-with-rai-injection","safety":{"commonSideEffects":[{"rate":"10-30","effect":"Hypoglycemia"},{"rate":"5-10","effect":"Injection site reactions"},{"rate":"2-5","effect":"Weight gain"},{"rate":"1-3","effect":"Lipodystrophy"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Insulin detemir is a long-acting basal insulin analog that binds to insulin receptors to facilitate glucose uptake and utilization in peripheral tissues. The addition of RAI (radioactive iodine) to an insulin injection is highly unusual and not a standard pharmaceutical formulation; RAI is typically administered orally or as a separate therapeutic agent for thyroid conditions, not mixed with insulin injections.","oneSentence":"Insulin detemir provides basal insulin replacement by binding to the insulin receptor, while RAI (radioactive iodine) component is unclear in this context as RAI is typically used for thyroid ablation, not diabetes management.","_ai_confidence":"low"},"_scrapedAt":"2026-03-27T23:49:12.897Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Type 1 diabetes mellitus"},{"name":"Type 2 diabetes mellitus"}]},"trialDetails":[{"nctId":"NCT00564395","phase":"PHASE4","title":"Detemir: Role in Type 1 Diabetes","status":"COMPLETED","sponsor":"Montefiore Medical Center","startDate":"2007-08","conditions":"Type 1 Diabetes Mellitus","enrollment":18}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Insulin Detemir mixed with RAI injection","genericName":"Insulin Detemir mixed with RAI injection","companyName":"Montefiore Medical Center","companyId":"montefiore-medical-center","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Insulin detemir provides basal insulin replacement by binding to the insulin receptor, while RAI (radioactive iodine) component is unclear in this context as RAI is typically used for thyroid ablation, not diabetes management. Used for Type 1 diabetes mellitus, Type 2 diabetes mellitus.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}