{"id":"infectoscab-5-creme","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation"},{"rate":null,"effect":"Pruritus"},{"rate":null,"effect":"Erythema"},{"rate":null,"effect":"Contact dermatitis"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The active ingredient (likely permethrin or benzyl benzoate based on standard scabicide formulations) disrupts the mite's nervous system by interfering with sodium channel function, leading to paralysis and death. The cream formulation allows for topical application directly to affected skin areas, providing localized treatment with minimal systemic absorption.","oneSentence":"InfectoScab 5% Creme is a topical scabicide that kills the Sarcoptes scabiei mite and its eggs through direct contact and penetration of the mite's exoskeleton.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:16:02.156Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Scabies (Sarcoptes scabiei infestation)"}]},"trialDetails":[{"nctId":"NCT06380452","phase":"PHASE3","title":"Therapy for Scabies With Two Differently Concentrated Permethrin Creams","status":"NOT_YET_RECRUITING","sponsor":"Infectopharm Arzneimittel GmbH","startDate":"2024-05","conditions":"Scabies","enrollment":220},{"nctId":"NCT04814511","phase":"PHASE3","title":"Escalated Therapy of Scabies With INFECTOSCAB 5% (Permethrin)","status":"UNKNOWN","sponsor":"Infectopharm Arzneimittel GmbH","startDate":"2021-06-11","conditions":"Scabies","enrollment":183}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"InfectoScab 5 % Creme","genericName":"InfectoScab 5 % Creme","companyName":"Infectopharm Arzneimittel GmbH","companyId":"infectopharm-arzneimittel-gmbh","modality":"Small molecule","firstApprovalDate":"","aiSummary":"InfectoScab 5% Creme is a topical scabicide that kills the Sarcoptes scabiei mite and its eggs through direct contact and penetration of the mite's exoskeleton. Used for Scabies (Sarcoptes scabiei infestation).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}