{"id":"imprimis-less-drops","safety":{"commonSideEffects":[{"rate":null,"effect":"Ocular irritation"},{"rate":null,"effect":"Transient stinging or burning"},{"rate":null,"effect":"Conjunctival hyperemia"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This is a customized eye drop preparation compounded by Imprimis Pharmaceuticals for individual patients. The formulation typically contains anti-inflammatory and lubricating agents tailored to patient-specific needs. It is part of the 'Less Drops' line, which aims to minimize the number of daily instillations required while maintaining therapeutic efficacy.","oneSentence":"Imprimis Less Drops is a compounded ophthalmic formulation designed to reduce ocular surface inflammation and provide symptomatic relief in dry eye disease.","_ai_confidence":"low"},"_scrapedAt":"2026-03-27T23:48:21.746Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry eye disease (keratoconjunctivitis sicca)"},{"name":"Ocular surface inflammation"}]},"trialDetails":[{"nctId":"NCT02819908","phase":"PHASE4","title":"Dropless™ vs. Less Drops™ Pharmaceutical Regimens After Cataract Surgery","status":"COMPLETED","sponsor":"Eye Center of North Florida","startDate":"2015-09","conditions":"Intraocular Lens Associated Postoperative Inflammation","enrollment":25}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Imprimis Less Drops","genericName":"Imprimis Less Drops","companyName":"Eye Center of North Florida","companyId":"eye-center-of-north-florida","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Imprimis Less Drops is a compounded ophthalmic formulation designed to reduce ocular surface inflammation and provide symptomatic relief in dry eye disease. Used for Dry eye disease (keratoconjunctivitis sicca), Ocular surface inflammation.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}