{"id":"imescard-compound-water-smartweed-ointment","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Smartweed (Polygonum species) contains polyphenolic compounds and flavonoids with documented anti-inflammatory and antimicrobial properties. When formulated as a topical ointment, these constituents are believed to reduce local inflammation, promote tissue repair, and potentially enhance wound healing through multiple phytochemical pathways. The exact active constituents and their precise molecular targets in this specific formulation are not well-characterized in published literature.","oneSentence":"An herbal ointment formulation containing smartweed (Polygonum) compounds that likely exerts anti-inflammatory and wound-healing effects through topical application.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:15:43.750Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Topical wound healing and inflammatory skin conditions (specific indication unclear from available data)"}]},"trialDetails":[{"nctId":"NCT00935948","phase":"PHASE3","title":"Efficacy and Safety Evaluation of the Imescard Compound Water Smartweed Ointment","status":"UNKNOWN","sponsor":"Hospital de Clinicas de Porto Alegre","startDate":"2008-04","conditions":"Hemorrhoidal Disease","enrollment":60}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Imescard","Water smartweed ointment"],"phase":"phase_3","status":"active","brandName":"Imescard compound water smartweed ointment","genericName":"Imescard compound water smartweed ointment","companyName":"Hospital de Clinicas de Porto Alegre","companyId":"hospital-de-clinicas-de-porto-alegre","modality":"Small molecule","firstApprovalDate":"","aiSummary":"An herbal ointment formulation containing smartweed (Polygonum) compounds that likely exerts anti-inflammatory and wound-healing effects through topical application. Used for Topical wound healing and inflammatory skin conditions (specific indication unclear from available data).","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}