{"id":"idp-120-gel","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation"},{"rate":null,"effect":"Erythema"},{"rate":null,"effect":"Dryness"},{"rate":null,"effect":"Peeling"}]},"_chembl":{"chemblId":"CHEMBL481680","moleculeType":"Small molecule","molecularWeight":"316.57"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"IDP-120 Gel contains a retinoid active pharmaceutical ingredient delivered in a gel formulation for topical application. Retinoids work by binding to retinoid receptors in skin cells, promoting differentiation and reducing comedone formation. This mechanism helps normalize keratinization and reduce inflammatory acne lesions.","oneSentence":"IDP-120 Gel is a topical retinoid formulation designed to treat acne and other skin conditions by promoting cell turnover and reducing sebum production.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:15:27.350Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acne vulgaris"}]},"trialDetails":[{"nctId":"NCT03664739","phase":"PHASE3","title":"Study Comparing the Safety and Efficacy of IDP-120 Gel and IDP-120 Vehicle Gel in the Treatment of Acne Vulgaris","status":"COMPLETED","sponsor":"Bausch Health Americas, Inc.","startDate":"2018-12-05","conditions":"Acne Vulgaris","enrollment":608},{"nctId":"NCT03664752","phase":"PHASE3","title":"Study Comparing the Safety and Efficacy of IDP-120 Gel and IDP-120 Vehicle Gel in the Treatment of Acne Vulgaris","status":"COMPLETED","sponsor":"Bausch Health Americas, Inc.","startDate":"2018-12-10","conditions":"Acne Vulgaris","enrollment":585},{"nctId":"NCT03003247","phase":"PHASE2","title":"Efficacy and Safety of IDP-120 Gel in the Treatment of Acne Vulgaris","status":"COMPLETED","sponsor":"Bausch Health Americas, Inc.","startDate":"2015-11","conditions":"Acne Vulgaris","enrollment":364},{"nctId":"NCT02850003","phase":"PHASE1","title":"Absorption and Systematic Pharmacokinetics of Topically Applied IDP-120 Gel","status":"COMPLETED","sponsor":"Bausch Health Americas, Inc.","startDate":"2016-06","conditions":"Acne","enrollment":20},{"nctId":"NCT02537483","phase":"PHASE2","title":"A Study Comparing the Efficacy and Safety of IDP-120 Gel in the Treatment of Acne Vulgaris","status":"UNKNOWN","sponsor":"Valeant Pharmaceuticals","startDate":"2015-10","conditions":"Acne Vulgaris","enrollment":350}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":334928,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Component A + B","Gel"],"phase":"phase_3","status":"active","brandName":"IDP-120 Gel","genericName":"IDP-120 Gel","companyName":"Bausch Health Americas, Inc.","companyId":"bausch-health-americas-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"IDP-120 Gel is a topical retinoid formulation designed to treat acne and other skin conditions by promoting cell turnover and reducing sebum production. Used for Acne vulgaris.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":2,"withResults":2},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}