{"id":"hyperpolarized-13c-15n2-urea","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL2096648","moleculeType":"Small molecule","molecularWeight":"61.05"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This agent works by exploiting the unique properties of hyperpolarized carbon-13 to create high-contrast images of metabolic activity in tissues. This allows for the non-invasive assessment of various physiological processes, such as glucose metabolism in cancer cells.","oneSentence":"Hyperpolarized 13C,15N2-urea is a diagnostic imaging agent that uses hyperpolarized carbon-13 to enhance the visibility of metabolic processes in the body.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:34:25.199Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Assessment of tumor metabolism in patients with cancer"}]},"trialDetails":[{"nctId":"NCT04258462","phase":"PHASE2","title":"Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Renal Tumors","status":"ACTIVE_NOT_RECRUITING","sponsor":"Zhen Wang, MD","startDate":"2019-01-15","conditions":"Benign Kidney Neoplasm, Kidney Neoplasm, Renal Cell Cancer","enrollment":54},{"nctId":"NCT02526368","phase":"EARLY_PHASE1","title":"Pilot Study of (MR) Imaging with Pyruvate (13C) to Detect High Grade Prostate Cancer","status":"RECRUITING","sponsor":"Ivan de Kouchkovsky, MD","startDate":"2016-03-22","conditions":"Prostate Cancer, Localized Prostate Carcinoma","enrollment":80}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Urea C-13","C13 Urea","HP 13C, 15N2"],"phase":"phase_2","status":"active","brandName":"Hyperpolarized 13C,15N2-urea","genericName":"Hyperpolarized 13C,15N2-urea","companyName":"Ivan de Kouchkovsky, MD","companyId":"ivan-de-kouchkovsky-md","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Hyperpolarized 13C,15N2-urea is a diagnostic imaging agent that uses hyperpolarized carbon-13 to enhance the visibility of metabolic processes in the body. Used for Assessment of tumor metabolism in patients with cancer.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":2,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}