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This allows for localized anesthesia in a specific anatomical region.","oneSentence":"Prilocaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of action potentials.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:41:25.701Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Local and regional anesthesia for surgical and diagnostic procedures"},{"name":"Spinal anesthesia"}]},"trialDetails":[{"nctId":"NCT05609565","phase":"PHASE4","title":"Intrathecal Prilocaine and Adductor Canal Block vs Intrathecal Bupivacaine Alone for Ambulatory Knee Arthroscopy","status":"COMPLETED","sponsor":"Ain Shams University","startDate":"2022-11-15","conditions":"Post Operative Pain","enrollment":80},{"nctId":"NCT06702202","phase":"NA","title":"Effect of Subarachnoid Block and Femoropopliteal Block to Limb Perfusion in PAD Patients","status":"COMPLETED","sponsor":"Indonesia University","startDate":"2024-01-01","conditions":"Peripheral Arterial Disease, Subarachnoid Block, Femoropopliteal Block","enrollment":16},{"nctId":"NCT05834647","phase":"PHASE4","title":"Efficacy and Safety of Prilocaine 2% and Lidocaine 5% Hyperbaric Against Spinal Anesthesia in Post Cystoscopy Procedure","status":"UNKNOWN","sponsor":"Universitas Sebelas Maret","startDate":"2023-08-01","conditions":"Anesthesia; Reaction, Anesthesia","enrollment":45},{"nctId":"NCT05751148","phase":"NA","title":"Cardiovascular Effects of Intrathecal Hyperbaric Prilocaine or Bupivacaine in Surgery Under Spinal Anesthesia","status":"UNKNOWN","sponsor":"Centre Hospitalier Universitaire Saint Pierre","startDate":"2023-03-22","conditions":"Spinal Anesthesia, Cardiac Toxicity","enrollment":60},{"nctId":"NCT03219086","phase":"NA","title":"Spinal Prilocaine for Caesarian Sections","status":"COMPLETED","sponsor":"University Hospital, Antwerp","startDate":"2017-08-01","conditions":"Combined Spinal Epidural Anesthesia, Prilocaine, Bupivacaine","enrollment":182},{"nctId":"NCT02973048","phase":"PHASE3","title":"Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine 2% for Cesarean Section Under Spinal Anesthesia","status":"COMPLETED","sponsor":"Centre Hospitalier Universitaire Saint Pierre","startDate":"2018-03-12","conditions":"Pregnant Women, Pain, Hypotension","enrollment":40},{"nctId":"NCT03036384","phase":"PHASE2","title":"Estimation of the ED95 of Intrathecal Hyperbaric Prilocaine 2% With Sufentanyl for Scheduled Cesarean Delivery","status":"COMPLETED","sponsor":"Centre Hospitalier Universitaire Saint Pierre","startDate":"2016-03","conditions":"Pregnant Women","enrollment":40},{"nctId":"NCT03607916","phase":"PHASE2","title":"Estimation of the Effective Dose (ED) 95 of Intrathecal Hyperbaric Prilocaine 2% for Scheduled Cesarean Delivery.","status":"COMPLETED","sponsor":"Centre Hospitalier Universitaire Saint Pierre","startDate":"2014-02","conditions":"Pregnant Women","enrollment":40},{"nctId":"NCT02384915","phase":"PHASE4","title":"Spinal Anesthesia Versus Combined Sciatic-femoral Nerve Block for Outpatient Knee Arthroscopy","status":"COMPLETED","sponsor":"ASST Gaetano Pini-CTO","startDate":"2015-01","conditions":"Knee Arthritis","enrollment":100},{"nctId":"NCT01921231","phase":"PHASE4","title":"Selective Subarachnoid Anesthesia. 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Used for Local and regional anesthesia for surgical and diagnostic procedures, Spinal anesthesia.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}