{"id":"hydroxyestrone-diacetate","rwe":[],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"colpormon","offLabel":[],"synonyms":["colpormon","colpogynon","hydroxyestrone diacetate"],"timeline":[],"approvals":[],"brandName":"Colpormon","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine estrogen as a key that unlocks specific doors in your cells. Colpormon is a modified version of this key that can fit into those doors and potentially change how they work. This could affect various bodily functions, such as growth and development, but the exact effects are still unknown.","oneSentence":"Colpormon works by interacting with estrogen receptors in the body, potentially influencing various physiological processes.","technicalDetail":"As a small molecule modality, Colpormon is likely to exert its effects through binding to estrogen receptors, potentially influencing gene expression and downstream signaling pathways."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Hydroxyestrone_diacetate","title":"Hydroxyestrone diacetate","extract":"Hydroxyestrone diacetate, or 16α-hydroxyestrone diacetate, also known as 3,16α-dihydroxyestra-1,3,5(10)-trien-17-one 3,16α-diacetate, is a synthetic, steroidal estrogen which has been marketed in France, Spain, Brazil, and Argentina. It is a derivative of 16α-hydroxyestrone with an acetate esters attached at the C3 and C16α positions."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3115","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=hydroxyestrone diacetate","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Hydroxyestrone_diacetate","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T13:54:10.910567","biosimilars":[],"competitors":[],"genericName":"hydroxyestrone diacetate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"005254","UNII":"2U3VOE52DG","CHEBI":"CHEBI:135562","RXNORM":"236161","UMLSCUI":"C0771407","PUBCHEM_CID":"102046","MESH_SUPPLEMENTAL_RECORD_UI":"C020756"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Colpormon is a synthetic, steroidal estrogen that has been marketed in several countries, including France, Spain, Brazil, and Argentina. It is a derivative of 16α-hydroxyestrone with acetate esters attached at the C3 and C16α positions.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}