{"id":"hydroeye","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Fishy aftertaste"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The supplement provides essential fatty acids and micronutrients that support meibomian gland function and tear production. By improving the lipid layer of the tear film, it helps reduce evaporation and provides symptomatic relief in dry eye disease. The formulation is intended to address the nutritional deficiencies that may contribute to aqueous tear deficiency and meibomian gland dysfunction.","oneSentence":"HydroEye® is an oral nutritional supplement containing omega-3 fatty acids and other nutrients designed to support tear film stability and reduce dry eye symptoms.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:40:12.618Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry eye disease / Keratoconjunctivitis sicca"}]},"trialDetails":[{"nctId":"NCT04163328","phase":"PHASE4","title":"Effects of Supplementation With PUFAs and Antioxidants for Contact Lens Discomfort","status":"TERMINATED","sponsor":"University of Alabama at Birmingham","startDate":"2022-09-16","conditions":"Dry Eye, Contact Lens Complication","enrollment":31}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"HydroEye®","genericName":"HydroEye®","companyName":"University of Alabama at Birmingham","companyId":"university-of-alabama-at-birmingham","modality":"Small molecule","firstApprovalDate":"","aiSummary":"HydroEye® is an oral nutritional supplement containing omega-3 fatty acids and other nutrients designed to support tear film stability and reduce dry eye symptoms. Used for Dry eye disease / Keratoconjunctivitis sicca.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}