{"id":"hyaluronic-acid-filler-imd1-basic","safety":{"commonSideEffects":[{"rate":"10-30","effect":"Injection site swelling"},{"rate":"5-20","effect":"Injection site erythema"},{"rate":"5-15","effect":"Bruising"},{"rate":"5-10","effect":"Tenderness at injection site"},{"rate":"<1","effect":"Nodule formation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Hyaluronic acid is a naturally occurring polysaccharide that acts as a humectant, drawing and retaining water in the skin. When injected as a dermal filler, it physically restores lost volume in facial tissues and simultaneously hydrates the surrounding dermis, smoothing wrinkles and restoring facial contours. The filler gradually biodegrades over time as the body metabolizes the hyaluronic acid.","oneSentence":"Hyaluronic acid filler provides volumization and hydration to facial tissues by integrating into the dermis and binding water molecules.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:39:51.973Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Facial wrinkles and folds correction"},{"name":"Lip augmentation"},{"name":"Facial volume restoration"}]},"trialDetails":[{"nctId":"NCT00429520","phase":"PHASE4","title":"Hyaluronic Acid Filler IMD1 Basic for Correction of Nasolabial Folds","status":"COMPLETED","sponsor":"Merz Pharmaceuticals GmbH","startDate":"2005-12","conditions":"Nasolabial Folds","enrollment":114}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Hyaluronic acid filler/IMD1 basic","genericName":"Hyaluronic acid filler/IMD1 basic","companyName":"Merz Pharmaceuticals GmbH","companyId":"merz-pharmaceuticals-gmbh","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Hyaluronic acid filler provides volumization and hydration to facial tissues by integrating into the dermis and binding water molecules. Used for Facial wrinkles and folds correction, Lip augmentation, Facial volume restoration.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}