{"id":"hyalein-mini-ophthalmic-solution","safety":{"commonSideEffects":[{"rate":null,"effect":"Ocular irritation"},{"rate":null,"effect":"Blurred vision"},{"rate":null,"effect":"Eye discomfort"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Hyaluronic acid is a naturally occurring polysaccharide that acts as a viscoelastic lubricant, reducing friction and providing moisture to the cornea and conjunctiva. It forms a protective film on the eye surface, promoting epithelial healing and reducing irritation associated with dry eye disease and post-operative ocular surface damage.","oneSentence":"Hyalein Mini is a hyaluronic acid-based ophthalmic solution that lubricates and protects the ocular surface.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:47:38.997Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry eye disease"},{"name":"Post-operative ocular surface protection"}]},"trialDetails":[{"nctId":"NCT06388070","phase":"PHASE3","title":"To Evaluate the Efficacy and Safety of HUC3-053 in Patients With Dry Eye Syndrome","status":"COMPLETED","sponsor":"Huons Co., Ltd.","startDate":"2024-05-20","conditions":"Dry Eye Syndromes","enrollment":297},{"nctId":"NCT00885079","phase":"PHASE3","title":"Confirmatory Study of OPC-12759 Ophthalmic Suspension","status":"COMPLETED","sponsor":"Otsuka Pharmaceutical Co., Ltd.","startDate":"2009-05","conditions":"Dry Eye Syndromes","enrollment":188}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Hyalein Mini Ophthalmic solution","genericName":"Hyalein Mini Ophthalmic solution","companyName":"Otsuka Pharmaceutical Co., Ltd.","companyId":"otsuka","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Hyalein Mini Ophthalmic solution is used to treat Dry Eye Syndromes. It is an oligosaccharide modality, specifically an oligosaccharide with anticoagulant properties similar to heparin.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}