{"id":"hp-802-247","safety":{"commonSideEffects":[{"rate":"null","effect":"Fatigue"},{"rate":"null","effect":"Nausea"},{"rate":"null","effect":"Diarrhea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"CD47 is a protein that inhibits phagocytosis, and blocking it can stimulate the immune system to attack cancer cells. HP-802-247 works by binding to CD47 and preventing it from interacting with its receptor, SIRPα, which is found on the surface of immune cells.","oneSentence":"HP-802-247 is a monoclonal antibody targeting CD47.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:47:56.000Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Relapsed or refractory multiple myeloma"}]},"trialDetails":[{"nctId":"NCT00900029","phase":"","title":"Safety Follow-Up to HP 802-247-09-015","status":"COMPLETED","sponsor":"Healthpoint","startDate":"2009-06","conditions":"Venous Leg Ulcer, Venous Stasis Ulcer","enrollment":206},{"nctId":"NCT01359735","phase":"PHASE2","title":"Healing Effects of HP802-247 Versus Antibiotic Ointment in Mohs Micrographic Surgery Patients","status":"COMPLETED","sponsor":"Healthpoint","startDate":"2011-05","conditions":"Non-melanoma Skin Cancer","enrollment":8},{"nctId":"NCT01656889","phase":"PHASE3","title":"Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers","status":"COMPLETED","sponsor":"Healthpoint","startDate":"2012-08","conditions":"Venous Leg Ulcers","enrollment":447}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"HP-802-247","genericName":"HP-802-247","companyName":"Healthpoint","companyId":"healthpoint","modality":"Biologic","firstApprovalDate":"","aiSummary":"HP-802-247 is a monoclonal antibody targeting CD47. Used for Relapsed or refractory multiple myeloma.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}