{"id":"homologated-placebo","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL4297922","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Homologated placebos are specially prepared inactive formulations used in Phase 3 randomized controlled trials to maintain blinding and reduce bias. They contain no active pharmaceutical ingredient but are manufactured to be indistinguishable from the active comparator in terms of organoleptic properties, packaging, and administration route, ensuring that neither patients nor investigators can identify treatment assignment.","oneSentence":"A homologated placebo is an inert control substance formulated to match the appearance, taste, and physical properties of an active investigational drug for blinded clinical trial purposes.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:45:03.688Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[]},"trialDetails":[{"nctId":"NCT04341571","phase":"PHASE2","title":"Effect of Probiotics Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes.","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of Guadalajara","startDate":"2019-10-24","conditions":"PreDiabetes, Impaired Glucose Tolerance, Hyperglycemia","enrollment":30},{"nctId":"NCT03613740","phase":"PHASE2","title":"Effect of Fucoxanthin on the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion","status":"COMPLETED","sponsor":"University of Guadalajara","startDate":"2019-09-30","conditions":"Metabolic Syndrome","enrollment":28},{"nctId":"NCT06061926","phase":"PHASE2","title":"Effect of Celery Seed on the Components of Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion","status":"RECRUITING","sponsor":"University of Guadalajara","startDate":"2023-05-20","conditions":"Metabolic Syndrome","enrollment":28},{"nctId":"NCT02305173","phase":"PHASE3","title":"Dexamethasone and Respiratory Function After Mastectomy","status":"COMPLETED","sponsor":"Instituto Mexicano del Seguro Social","startDate":"2014-11","conditions":"Respiratory; Disorder, Functional, Impaired","enrollment":120},{"nctId":"NCT04011618","phase":"PHASE2","title":"Effect of Ellagic Ácid on the Components of Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion","status":"UNKNOWN","sponsor":"University of Guadalajara","startDate":"2019-09-17","conditions":"Metabolic Syndrome","enrollment":32},{"nctId":"NCT03848533","phase":"PHASE2","title":"Effect of Melatonin and Metformin on Glycemic Control Genotoxicity and Cytotoxicity Markers in Patients With Prediabetes","status":"UNKNOWN","sponsor":"University of Guadalajara","startDate":"2019-08-22","conditions":"PreDiabetes","enrollment":42},{"nctId":"NCT02522117","phase":"PHASE3","title":"Atorvastatin in the Recipient's Kidney Graft From a Living Donor","status":"COMPLETED","sponsor":"Instituto Mexicano del Seguro Social","startDate":"2015-08","conditions":"Renal Insufficiency","enrollment":48},{"nctId":"NCT02355704","phase":"PHASE3","title":"Anti-inflammatory Effect of Atorvastatin on Graft Donor Kidney","status":"COMPLETED","sponsor":"Instituto Mexicano del Seguro Social","startDate":"2012-01","conditions":"Renal Insufficiency","enrollment":48},{"nctId":"NCT02328144","phase":"PHASE3","title":"Effectiveness of Metronidazole in Pain Control Posthemorrhoidectomy","status":"COMPLETED","sponsor":"Instituto Mexicano del Seguro Social","startDate":"2013-07","conditions":"Hemorrhoids","enrollment":44},{"nctId":"NCT01116713","phase":"PHASE3","title":"Effect of Dexamethasone in Postoperative Symptoms After Mastectomy for Breast Cancer","status":"COMPLETED","sponsor":"Instituto Mexicano del Seguro Social","startDate":"2009-06","conditions":"Postoperative Pain, Postoperative Nausea, Postoperative Vomiting","enrollment":70}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":4,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["no other intervention"],"phase":"phase_3","status":"active","brandName":"Homologated placebo.","genericName":"Homologated placebo.","companyName":"Instituto Mexicano del Seguro Social","companyId":"instituto-mexicano-del-seguro-social","modality":"Small molecule","firstApprovalDate":"","aiSummary":"","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}