{"id":"homochlorcyclizine","rwe":[{"pmid":"41318154","year":"2025","title":"Homochlorcyclizine Dihydrochloride Inhibits Hepatocellular Carcinoma Progression and Cancer Stem Cell Properties.","finding":"","journal":"Anticancer research","studyType":"Clinical Study"},{"pmid":"41286270","year":"2025","title":"Pan-cancer analysis identified DOK3 as a novel biomarker for predicting prognosis and immunotherapy effectiveness.","finding":"","journal":"Discover oncology","studyType":"Clinical Study"},{"pmid":"36867725","year":"2023","title":"Synthesis of 1,4-Diazacycles by Hydrogen Borrowing.","finding":"","journal":"Organic letters","studyType":"Clinical Study"},{"pmid":"26896646","year":"2016","title":"Bioavailable inhibitors of HIV-1 RNA biogenesis identified through a Rev-based screen.","finding":"","journal":"Biochemical pharmacology","studyType":"Clinical Study"},{"pmid":"22297750","year":"2012","title":"Inhibitory effect of homochlorcyclizine on melanogenesis in α-melanocyte stimulating hormone-stimulated mouse B16 melanoma cells.","finding":"","journal":"Archives of pharmacal research","studyType":"Clinical Study"}],"tags":[{"label":"homochlorcyclizine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"homodamon","offLabel":[],"synonyms":["homochlorcyclizine","homochlorocyclizine","homoclomine","homodamon","homochlorcyclizine dihydrochloride"],"timeline":[],"approvals":[],"brandName":"Homodamon","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"homochlorcyclizine","explanation":"Imagine your body's cells are like locks, and Homodamon is a key that fits into one of those locks. When it binds to the lock, it can affect how the cell works, but we don't know exactly how it does that yet. More research is needed to understand how Homodamon interacts with cells and what effects it has on the body.","oneSentence":"Homodamon works by interacting with a specific target in the body, although the exact mechanism is currently unknown.","technicalDetail":"Homodamon's mechanism of action is currently unknown, and further research is needed to determine its pharmacological properties and potential therapeutic applications."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1381","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=HOMOCHLORCYCLIZINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:54:07.454477","biosimilars":[],"competitors":[],"genericName":"homochlorcyclizine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"015084","UNII":"N5MVC31W2N","CHEBI":"CHEBI:91588","INN_ID":"934","UMLSCUI":"C0163772","ChEMBL_ID":"CHEMBL1515447","KEGG_DRUG":"D08041","DRUGBANK_ID":"DB15979","PUBCHEM_CID":"3627","SECONDARY_CAS_RN":"1982-36-1","MESH_SUPPLEMENTAL_RECORD_UI":"C034022"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":31,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2025 Dec","pmid":"41318154","title":"Homochlorcyclizine Dihydrochloride Inhibits Hepatocellular Carcinoma Progression and Cancer Stem Cell Properties.","journal":"Anticancer research"},{"date":"2025 Nov 24","pmid":"41286270","title":"Pan-cancer analysis identified DOK3 as a novel biomarker for predicting prognosis and immunotherapy effectiveness.","journal":"Discover oncology"},{"date":"2023 Mar 17","pmid":"36867725","title":"Synthesis of 1,4-Diazacycles by Hydrogen Borrowing.","journal":"Organic letters"},{"date":"2016 May 1","pmid":"26896646","title":"Bioavailable inhibitors of HIV-1 RNA biogenesis identified through a Rev-based screen.","journal":"Biochemical pharmacology"},{"date":"2012 Jan","pmid":"22297750","title":"Inhibitory effect of homochlorcyclizine on melanogenesis in α-melanocyte stimulating hormone-stimulated mouse B16 melanoma cells.","journal":"Archives of pharmacal research"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Homodamon is a small molecule with synonyms including CUROSAJIN, HOMOCHLORCYCLIZINE, and others. Its exact mechanism and indications are not specified in the provided information.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}