{"id":"high-dose-vitamin-c","safety":{"commonSideEffects":[{"rate":null,"effect":"Infusion site reactions"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Fatigue"},{"rate":null,"effect":"Hyperglycemia (in susceptible patients)"},{"rate":null,"effect":"Kidney stone formation (with chronic use)"}]},"_chembl":{"chemblId":"CHEMBL196","moleculeType":"Small molecule","molecularWeight":"176.12"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"At high concentrations achieved through intravenous administration, ascorbic acid generates hydrogen peroxide and other reactive oxygen species that preferentially accumulate in tumor cells due to their altered metabolism, leading to oxidative stress and cell death. 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