{"id":"hidrosmin","rwe":[{"pmid":"40348378","year":"2025","title":"The role of venoactive compounds in the treatment of chronic venous disease.","finding":"","journal":"Journal of vascular surgery. Venous and lymphatic disorders","studyType":"Clinical Study"},{"pmid":"40101859","year":"2025","title":"Utility of venoactive compounds in post-thrombotic syndrome: A systematic review.","finding":"","journal":"Journal of vascular surgery. Venous and lymphatic disorders","studyType":"Clinical Study"},{"pmid":"37909541","year":"2024","title":"Repurposing FDA approved drug molecules against A B C classes of β-lactamases: a computational biology and molecular dynamics simulations study.","finding":"","journal":"Journal of biomolecular structure & dynamics","studyType":"Clinical Study"},{"pmid":"36757036","year":"2023","title":"WITHDRAWN: Hidrosmin Attenuates Inflammatory Response Induced by IL1β by Suppressing the Activation of NF-κB Involving Nrf2/HO1 Pathway in Human Osteoarthritis Chondrocytes.","finding":"","journal":"Current cancer drug targets","studyType":"Clinical Study"},{"pmid":"36552707","year":"2022","title":"The Synthetic Flavonoid Hidrosmin Improves Endothelial Dysfunction and Atherosclerotic Lesions in Diabetic Mice.","finding":"","journal":"Antioxidants (Basel, Switzerland)","studyType":"Clinical Study"}],"tags":[{"label":"hidrosmin","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"C05CA05","category":"atc"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"venosmil","offLabel":[],"synonyms":["hidrosmin","venosmil"],"timeline":[],"approvals":[],"brandName":"Venosmil","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"hidrosmin","explanation":"Imagine your blood vessels as roads in your body. Venosmil is believed to help improve the flow of traffic on these roads, making it easier for blood to reach all parts of your body. This can be especially helpful for people with conditions that affect blood flow.","oneSentence":"Venosmil is thought to work by influencing the body's natural processes to improve blood flow and circulation.","technicalDetail":"The exact mechanism of action of Venosmil is unknown, but it is thought to involve the modulation of endothelial function and the regulation of vascular tone."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3956","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=hidrosmin","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:53:18.541036","biosimilars":[],"competitors":[],"genericName":"hidrosmin","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"007245","UNII":"4I5K8199OQ","CHEBI":"CHEBI:135840","UMLSCUI":"C0121780","ChEMBL_ID":"CHEMBL3707286","DRUGBANK_ID":"DB13490","PUBCHEM_CID":"3087722","SNOMEDCT_US":"702796008","MESH_SUPPLEMENTAL_RECORD_UI":"C071047"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":14,"therapeuticAreas":["Hematology"],"atcClassification":{"source":"DrugCentral","atcCode":"C05CA05","allCodes":["C05CA05"]},"biosimilarFilings":[],"recentPublications":[{"date":"2025 Sep","pmid":"40348378","title":"The role of venoactive compounds in the treatment of chronic venous disease.","journal":"Journal of vascular surgery. Venous and lymphatic disorders"},{"date":"2025 Jul","pmid":"40101859","title":"Utility of venoactive compounds in post-thrombotic syndrome: A systematic review.","journal":"Journal of vascular surgery. Venous and lymphatic disorders"},{"date":"2024","pmid":"37909541","title":"Repurposing FDA approved drug molecules against A B C classes of β-lactamases: a computational biology and molecular dynamics simulations study.","journal":"Journal of biomolecular structure & dynamics"},{"date":"2023 Feb 9","pmid":"36757036","title":"WITHDRAWN: Hidrosmin Attenuates Inflammatory Response Induced by IL1β by Suppressing the Activation of NF-κB Involving Nrf2/HO1 Pathway in Human Osteoarthritis Chondrocytes.","journal":"Current cancer drug targets"},{"date":"2022 Dec 19","pmid":"36552707","title":"The Synthetic Flavonoid Hidrosmin Improves Endothelial Dysfunction and Atherosclerotic Lesions in Diabetic Mice.","journal":"Antioxidants (Basel, Switzerland)"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Venosmil is a flavonoid, specifically a flavone, that has vasoprotective properties.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}