{"id":"hh-120-nasal-spray","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Nasal irritation"},{"rate":"5-10%","effect":"Headache"},{"rate":"5-10%","effect":"Nausea"}]},"_chembl":{"chemblId":"CHEMBL3986852","moleculeType":"Small molecule","molecularWeight":"486.62"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"HH-120 Nasal Spray works by mimicking the effects of cortisol, a naturally occurring steroid in the body, to decrease swelling and inflammation in the nasal passages. This can help alleviate symptoms of nasal congestion, runny nose, and sneezing associated with allergic rhinitis and other conditions. By reducing inflammation, HH-120 Nasal Spray can also help prevent the growth of nasal polyps and reduce the risk of complications such as sinus infections.","oneSentence":"HH-120 Nasal Spray is a corticosteroid used to reduce inflammation in the nasal passages.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:15:08.122Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Allergic rhinitis"},{"name":"Nasal congestion"}]},"trialDetails":[{"nctId":"NCT05713318","phase":"PHASE2","title":"A Study To Assess The Efficacy and Safety of HH-120 Nasal Spray for the Treatment of Mild COVID-19","status":"COMPLETED","sponsor":"Huahui Health","startDate":"2023-01-18","conditions":"COVID-19","enrollment":200},{"nctId":"NCT05787418","phase":"PHASE3","title":"HH-120 Nasal Spray for Post-exposure Prevention of SARS-CoV-2","status":"ENROLLING_BY_INVITATION","sponsor":"Huahui Health","startDate":"2023-03-31","conditions":"COVID-19","enrollment":1200},{"nctId":"NCT05659602","phase":"NA","title":"A Clinical Study to Assess Preliminary Efficacy, Safety and Tolerability of HH-120 Nasal Spray in COVID-19 Patients","status":"COMPLETED","sponsor":"Beijing Ditan Hospital","startDate":"2022-07-09","conditions":"Coronavirus Disease 2019(COVID-19)","enrollment":111},{"nctId":"NCT05753878","phase":"PHASE1","title":"A Study to Evaluate the Safety and Pharmacokinetics of HH-120 Nasal Spray in Healthy Volunteers","status":"COMPLETED","sponsor":"Huahui Health","startDate":"2022-11-08","conditions":"COVID-19","enrollment":62},{"nctId":"NCT05765279","phase":"NA","title":"A Study to Assess the Efficacy of HH-120 Nasal Spray for Prevention of SARS-CoV-2 Infection in Adult Close Contacts of Individuals Infected With SARS-CoV-2","status":"COMPLETED","sponsor":"Beijing Ditan Hospital","startDate":"2022-10-20","conditions":"SARS-CoV-2 Infection","enrollment":281},{"nctId":"NCT05747677","phase":"NA","title":"A Study of HH-120 Nasal Spray in Close Contacts of Those Diagnosed With COVID-19","status":"COMPLETED","sponsor":"Beijing Ditan Hospital","startDate":"2022-06-14","conditions":"COVID-19, SARS-CoV-2 Infection","enrollment":14}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"HH-120 Nasal Spray","genericName":"HH-120 Nasal Spray","companyName":"Beijing Ditan Hospital","companyId":"beijing-ditan-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"HH-120 Nasal Spray is a corticosteroid used to reduce inflammation in the nasal passages. Used for Allergic rhinitis, Nasal congestion.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}